? ? There is increasing recognition that inflammatory processes underlie many acute and chronic diseases, including those of the central nervous system. In particular, the glial and vascular components of the brain play significant and unique roles in inflammatory processes, both as sources of inflammatory mediators and as targets for local innate and acquired immune responses. Moreover, there is increasing recognition of the importance for glia in all aspects of brain function, ranging from normal homeostasis to repair and repopulation following injury. Understanding these processes and their implications for diseases requires interactions that cross the classic disciplines of Neuroscience, Immunology, and Developmental Cell Biology, with focused training in molecular/immunological signaling and glial cell biology. Building on strengths of an outstanding group of faculty at the University of Rochester Medical Center, this grant application outlines a proposed program for pre and postdoctoral students that provides the cross-disciplinary exposure and highly interactive research environments required for scientists to access the fields of Neuroinflammation and Glial Cell Biology. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
1T32NS051152-01
Application #
6894889
Study Section
NST-2 Subcommittee (NST)
Program Officer
Korn, Stephen J
Project Start
2005-07-01
Project End
2010-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
1
Fiscal Year
2005
Total Cost
$182,133
Indirect Cost
Name
University of Rochester
Department
Neurosciences
Type
Schools of Dentistry
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627
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