Veterinary biomedical researchers greatly enhance animal-based research that serves as the key bridge connecting basic science and human-based studies. Veterinarian scientists play crucial roles by performing biomedical research and by developing, characterizing, and using animal models to study human diseases, enhancing rigor and reproducibility. Building on the outstanding foundation in comparative pathophysiology and medicine provided by DVM/VMD curricula, in-depth, rigorous training in biomedical research is ideal to foster research careers for veterinarians. This proposal seeks renewal of support for our highly productive NIH- funded T32 program led by Joseph L. Mankowski, DVM, PhD, to train veterinarians in biomedical research at the Johns Hopkins University School of Medicine. The primary goal of our program is to launch the careers of veterinarian-scientists. We request funding for six DVM/VMD trainee slots/year to provide 3 years of support/trainee. At Johns Hopkins, veterinarian trainees pursue research-intensive training by completing PhDs or research postdoctoral fellowships if they enter the program holding dual degrees (both DVM/VMD and PhD). We have a deep applicant pool to draw from to fill these positions. Our training program offers an outstanding career development opportunity for veterinarians passionate about building careers in biomedical research and becoming innovators and leaders in their fields. The great majority of trainees pursue either research-intensive or research-related careers after completing training.

Public Health Relevance

Veterinarian scientists play crucial roles by performing biomedical research and by developing, characterizing, and using animal models to study human diseases, thereby enhancing rigor and reproducibility. Our training program offers an outstanding career development opportunity for veterinarians passionate about building careers in biomedical research and becoming innovators and leaders in their research fields. This proposal seeks renewal of support for our highly productive NIH-funded T32 program led by Joseph L. Mankowski, DVM, PhD, to train veterinarians in biomedical research at the Johns Hopkins University School of Medicine.

Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
Institutional National Research Service Award (T32)
Project #
2T32OD011089-44
Application #
9854009
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Watson, Harold L
Project Start
1977-07-01
Project End
2025-05-31
Budget Start
2020-06-01
Budget End
2021-05-31
Support Year
44
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Veterinary Sciences
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Mangus, Lisa M; Beck, Sarah E; Queen, Suzanne E et al. (2018) Lymphocyte-Dominant Encephalitis and Meningitis in Simian Immunodeficiency Virus-Infected Macaques Receiving Antiretroviral Therapy. Am J Pathol 188:125-134
Beck, Sarah E; Queen, Suzanne E; Metcalf Pate, Kelly A et al. (2018) An SIV/macaque model targeted to study HIV-associated neurocognitive disorders. J Neurovirol 24:204-212
Baxter, Victoria K; Troisi, Elizabeth M; Pate, Nathan M et al. (2018) Death and gastrointestinal bleeding complicate encephalomyelitis in mice with delayed appearance of CNS IgM after intranasal alphavirus infection. J Gen Virol :
Nilaratanakul, Voraphoj; Chen, Jie; Tran, Oanh et al. (2018) Germ Line IgM Is Sufficient, but Not Required, for Antibody-Mediated Alphavirus Clearance from the Central Nervous System. J Virol 92:
Vermillion, Meghan S; Klein, Sabra L (2018) Pregnancy and infection: using disease pathogenesis to inform vaccine strategy. NPJ Vaccines 3:6
France, Logan K; Vermillion, Meghan S; Garrett, Caroline M (2018) Comparison of Direct and Indirect Methods of Measuring Arterial Blood Pressure in Healthy Male Rhesus Macaques (Macaca mulatta). J Am Assoc Lab Anim Sci 57:64-69
Vermillion, Meghan S; Ursin, Rebecca L; Attreed, Sarah E et al. (2018) Estriol Reduces Pulmonary Immune Cell Recruitment and Inflammation to Protect Female Mice From Severe Influenza. Endocrinology 159:3306-3320
Vermillion, Meghan S; Ursin, Rebecca L; Kuok, Denise I T et al. (2018) Production of amphiregulin and recovery from influenza is greater in males than females. Biol Sex Differ 9:24
Pierpont, Timothy M; Lyndaker, Amy M; Anderson, Claire M et al. (2017) Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer. Cell Rep 21:1896-1909
McPherson, Robert Lyle; Abraham, Rachy; Sreekumar, Easwaran et al. (2017) ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence. Proc Natl Acad Sci U S A 114:1666-1671

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