The National Research Council has documented a dire national need for veterinary specialists trained in biomedical research. Furthermore, veterinary researchers play a key role in comparative and translational research activities since they naturally bridge basic and clinical research. To address this training need, faculty in the Center for Comparative Medicine and Translational Research (CCMTR) at the College of Veterinary Medicine, North Carolina State University established the Comparative Medicine and Translational Research Training Program (CMTRTP). This training program specifically targets individuals with the DVM degree who have completed specialty training. Trainees complete requirements leading to the PhD degree in laboratories of well-funded faculty that have a strong track training record and diverse research expertise. Research projects emphasize comparative and translational themes fostered by the CCMTR and trainees participate in multidisciplinary research efforts. Trainees bridge research programs and serve as a nidus for new faculty collaborations. The training program was initiated in Fall 2007 with funds for 2 slots committed by North Carolina State University. Funding from an NIH T32 in 2008 enabled the program to grow to a total of 8 training slots. To date, we have recruited 12 outstanding trainees who by all accounts, are talented clinician scientists when the complete the program. For this renewal application, six trainee slots are requested in Year 1 of the next grant period to restore the NIH funded slots to the original level and 2 will be supported from NC State resources. We propose to grow the program to a total of 9 training slots by adding 1 additional NIH slot in Year 2. Program requirements include: (1) a capstone course on comparative medicine and translational research; (2) a professional development courses and workshops; (3) a seminar series on translational research; (4) a course in research ethics; (5) a pilot grant program that will culminate in submission of a K award proposal; and (6) an annual research symposium. These requirements are in addition to those associated with a student's graduate program. This novel training program will build upon the strong commitment and track record of the NC State CVM to train veterinary specialists in research.

Public Health Relevance

This training program in Comparative Medicine and Translational Research (CMTR) addresses two critical national needs in biomedical research. First is the growing need for Veterinarians with training in biomedical research. Second is that more emphasis needs to be placed on translation of basic research advances to the clinical setting and this often requires a multidisciplinary approach.

Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
Institutional National Research Service Award (T32)
Project #
4T32OD011130-09
Application #
9120944
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Moro, Manuel H
Project Start
2008-08-01
Project End
2018-07-31
Budget Start
2016-08-01
Budget End
2017-07-31
Support Year
9
Fiscal Year
2016
Total Cost
Indirect Cost
Name
North Carolina State University Raleigh
Department
Other Clinical Sciences
Type
Schools of Veterinary Medicine
DUNS #
042092122
City
Raleigh
State
NC
Country
United States
Zip Code
27695
Stieler Stewart, Amy; Freund, John M; Blikslager, Anthony T et al. (2018) Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia. J Vis Exp :
Lewis, Melissa J; Cohen, Eli B; Olby, Natasha J (2018) Magnetic resonance imaging features of dogs with incomplete recovery after acute, severe spinal cord injury. Spinal Cord 56:133-141
Stewart, A Stieler; Freund, J M; Gonzalez, L M (2018) Advanced three-dimensional culture of equine intestinal epithelial stem cells. Equine Vet J 50:241-248
Friedenberg, S G; Brown, D L; Meurs, K M et al. (2018) Lymphocyte Subsets in the Adrenal Glands of Dogs With Primary Hypoadrenocorticism. Vet Pathol 55:177-181
Gruen, Margaret E; Messenger, Kristen M; Thomson, Andrea E et al. (2017) Evaluation of serum cytokines in cats with and without degenerative joint disease and associated pain. Vet Immunol Immunopathol 183:49-59
Gruen, Margaret E; Griffith, Emily H; Caney, Sarah M A et al. (2017) Attitudes of small animal practitioners toward participation in veterinary clinical trials. J Am Vet Med Assoc 250:86-97
Lewis, Melissa J; Howard Jr, James F; Olby, Natasha J (2017) The Relationship between Trans-Lesional Conduction, Motor Neuron Pool Excitability, and Motor Function in Dogs with Incomplete Recovery from Severe Spinal Cord Injury. J Neurotrauma 34:2994-3002
Watson, Victoria E; Jacob, Megan E; Flowers, James R et al. (2017) Association of Atypical Enteropathogenic Escherichia coli with Diarrhea and Related Mortality in Kittens. J Clin Microbiol 55:2719-2735
Gruen, Margaret E; Alfaro-Córdoba, Marcela; Thomson, Andrea E et al. (2017) The Use of Functional Data Analysis to Evaluate Activity in a Spontaneous Model of Degenerative Joint Disease Associated Pain in Cats. PLoS One 12:e0169576
Friedenberg, Steven G; Lunn, Katharine F; Meurs, Kathryn M (2017) Evaluation of the genetic basis of primary hypoadrenocorticism in Standard Poodles using SNP array genotyping and whole-genome sequencing. Mamm Genome 28:56-65

Showing the most recent 10 out of 58 publications