We request support for 6 summer veterinary research fellowships at Wake Forest School of Medicine, as part of a multi-level training program in comparative medicine and research. The national shortage of veterinary scientists in biomedical research is well documented in terms of vacant veterinary research positions and unmet collaborative needs. This shortage has resulted in deficits in the quality of research findings and lost productivity among researchers using animals. Correcting the dearth of veterinary researchers requires education of veterinary students regarding research methods and opportunities and the unique value of their professional skills. Early exposure to research during veterinary school is the most promising strategy. Therefore, the proposed summer research program seeks to expose veterinary students to biomedical research through practical experience. Objectives are (1) To provide a structured summer research experience at Wake Forest School of Medicine;(2) to teach students in the program the basic elements of hypothesis-driven research, grant-writing, and data analysis;(3) to provide training in ethics and professionalism in research;and (4) to provide the students with experience in oral and written presentation of scientific findings. Training will be principally accomplished by one-on-one mentoring through completion of a research project guided by a senior researcher chosen from a pool of 28 program faculty (including 11 veterinarians) in diverse fields including pathology, comparative medicine, developmental psychology, behavior, substance abuse, surgery, physiology/pharmacology, neurobiology, rheumatology/immunology, hypertension, cardiovascular disease, diabetes, nutrition, cancer, radiation countermeasures, and reproductive medicine/obstetrics/gynecology/women's health. Students will also participate in a dedicated short course in research survival skills, and in ongoing seminars and journal clubs in the Section on Comparative Medicine. Students will write a research proposal and a final report of their findings, and will be encouraged to present their findings nationally and to publish. This program will provide opportunities for original scientific thought, ethical reflection, and acquisition of critical skills, in a setting uniquely supportive of veterinarians as independent researchers.

Public Health Relevance

There is a national shortage of veterinarians in research. This renewal application seeks to provide six veterinary students per year with a summer fellowship designed to teach them about research methods, ethics, and career opportunities in biomedical research.

National Institute of Health (NIH)
Office of The Director, National Institutes of Health (OD)
NRSA Short -Term Research Training (T35)
Project #
Application #
Study Section
Special Emphasis Panel (ZOD1-CM-6 (02))
Program Officer
Moro, Manuel H
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Wake Forest University Health Sciences
Schools of Medicine
United States
Zip Code
Tytell, Michael; Davis, Ashley T; Giles, Jareca et al. (2018) Alfalfa-derived HSP70 administered intranasally improves insulin sensitivity in mice. Cell Stress Chaperones 23:189-194
Farris, Michael; McTyre, Emory R; Okoukoni, Catherine et al. (2018) Cortical Thinning and Structural Bone Changes in Non-Human Primates after Single-Fraction Whole-Chest Irradiation. Radiat Res 190:63-71
Wilson, Quentin N; Wells, Magan; Davis, Ashley T et al. (2018) Greater Microbial Translocation and Vulnerability to Metabolic Disease in Healthy Aged Female Monkeys. Sci Rep 8:11373
Atkins, Hannah M; Appt, Susan E; Taylor, Robert N et al. (2018) Systemic Iron Deficiency in a Nonhuman Primate Model of Endometriosis. Comp Med 68:298-307
Fanning, K M; Pfisterer, B; Davis, A T et al. (2017) Changes in microvascular density differentiate metabolic health outcomes in monkeys with prior radiation exposure and subsequent skeletal muscle ECM remodeling. Am J Physiol Regul Integr Comp Physiol 313:R290-R297
Mitchell, E L; Davis, A T; Brass, K et al. (2017) Reduced Intestinal Motility, Mucosal Barrier Function, and Inflammation in Aged Monkeys. J Nutr Health Aging 21:354-361
Kavanagh, Kylie; Brown, Richelle N; Davis, Ashley T et al. (2016) Microbial translocation and skeletal muscle in young and old vervet monkeys. Age (Dordr) 38:58
Willard, Stephanie L; Uberseder, Beth; Clark, Ashlee et al. (2015) Long term sertraline effects on neural structures in depressed and nondepressed adult female nonhuman primates. Neuropharmacology 99:369-78
Kavanagh, Kylie; Dendinger, Michael D; Davis, Ashley T et al. (2015) Type 2 Diabetes is a Delayed Late Effect of Whole-Body Irradiation in Nonhuman Primates. Radiat Res 183:398-406
Silverstein, Marnie G; Ordanes, Diane; Wylie, Ashley T et al. (2015) Inducing Muscle Heat Shock Protein 70 Improves Insulin Sensitivity and Muscular Performance in Aged Mice. J Gerontol A Biol Sci Med Sci 70:800-8

Showing the most recent 10 out of 12 publications