Veterinarians are broadly trained health professionals uniquely qualified to participate in biomedical research, having an understanding of health and disease at the organismal level with an appreciation of comparative biology1,2.The ?One Health? concept, integrating discoveries in both human and veterinary medicine, has received increased attention with new and emerging zoonoses, as well as increasingly common chronic conditions (e.g., cardiovascular disease and diabetes mellitus), and increased concerns with the effects of environmental and dietary toxins on fetal and early stages of development. As translational research with animal models continue to expand to approximately half of all current NIH research projects1, veterinarians, particularly those with research training, make increasingly valuable contributions to biomedical research.3 Reports by National Academy of Sciences National Research Council Committees concluded that there is a critical shortage of such veterinarians4,5. The Texas A&M University summer Veterinary Student Research Training Program (VMSRTP) is evolving and expanding during our next T35 renewal period. In addition to our previous goal to introduce veterinary students to the biomedical research environment to entice trainees to discover research as an exciting career option, we will now expand our program recruitment efforts to include veterinary students who have previous research experience. Providing these experienced students with a robust summer biomedical research experience with experienced federally funded mentors and enhanced training in responsible conduct of research methods and scientific communication skills will likely enhance their individual research successes, and further establish their interest and commitment to veterinary careers in biomedical research. In this competitive renewal, the program will be led by a new Program Director, a new Program Coordinator, a reconfigured Advisory Committee, and a more focused research mentor base with 27 experienced mentors with strong federal extramural biomedical funding. The summer program includes: 1) biomedical research in a mentor?s laboratory; (2) at least 12 hours formal training in responsible conduct of research; (3) weekly lunchtime (hour-long) training sessions in scientific communication via oral and poster presentations, abstract and manuscript preparation, as well as training in critical evaluation and presentation of primary journal articles; (4) oral research presentations in the annual CVM research symposium; and 5) research poster presentations at the National Veterinary Scholars Symposium. The program has exceptional institutional support and a broad array of state-of-the-art facilities, including preclinical GLP labs, a national biodefense lab, primate center, strong institutional collaborations, and a recently funded DHHS Biodefense vaccine center. A major obstacle to the efforts of academic institutions to produce more research veterinarians is the difficulty of providing adequate salary sources to introduce trainees to research. The training positions provided by this T35 would assist recruiting efforts, increase numbers of veterinarians in research, and help alleviate this national shortage.
This Veterinary Student Research Training program (VSRTP) at Texas A&M University addresses a critical national need for veterinarians in biomedical research. Veterinarians have a unique understanding of health and disease at the organismal level of a variety of animal species, and increased numbers of veterinarians in research would alleviate this national shortage. Our evolving T35 programmatic goal is to stimulate veterinary students to consider a veterinary career in biomedical research by providing them with rich, immersive summer training experiences under the direction of NIH-funded mentors in robust biomedical research programs. In this T35 renewal, we will both facilitate novice trainees to discover research as an exciting career option, as well as further develop the research and scientific communication skillsets of trainees with previous research experience and help to solidify their interest and commitment to a veterinary career in biomedical research.
|Milligan, Sherrelle; Martin, Gregory G; Landrock, Danilo et al. (2018) Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice. Biochim Biophys Acta Mol Cell Biol Lipids 1863:323-338|
|Martin, Gregory G; Seeger, Drew R; McIntosh, Avery L et al. (2018) Scp-2/Scp-x ablation in Fabp1 null mice differentially impacts hepatic endocannabinoid level depending on dietary fat. Arch Biochem Biophys 650:93-102|
|Linden, Albert G; Li, Shili; Choi, Hwa Y et al. (2018) Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice. J Lipid Res 59:475-487|
|Meason-Smith, Courtney; Edwards, Erin E; Older, Caitlin E et al. (2017) Panfungal Polymerase Chain Reaction for Identification of Fungal Pathogens in Formalin-Fixed Animal Tissues. Vet Pathol 54:640-648|
|Martin, Gregory G; Landrock, Danilo; Chung, Sarah et al. (2017) Loss of fatty acid binding protein-1 alters the hepatic endocannabinoid system response to a high-fat diet. J Lipid Res 58:2114-2126|
|Hodo, Carolyn L; Bertolini, Nicole R; Bernal, John C et al. (2017) Lack of Trypanosoma cruzi Infection in Urban Roof Rats (Rattus rattus) at a Texas Facility Housing Naturally Infected Nonhuman Primates. J Am Assoc Lab Anim Sci 56:57-62|
|Chatham-Stephens, Kevin; Taylor, Ethel; Chang, Arthur et al. (2017) Hepatotoxicity associated with weight loss or sports dietary supplements, including OxyELITE Pro™ - United States, 2013. Drug Test Anal 9:68-74|
|Martin, Gregory G; Landrock, Danilo; Chung, Sarah et al. (2017) Fabp1 gene ablation inhibits high-fat diet-induced increase in brain endocannabinoids. J Neurochem 140:294-306|
|Meason-Smith, Courtney; Diesel, Alison; Patterson, Adam P et al. (2017) Characterization of the cutaneous mycobiota in healthy and allergic cats using next generation sequencing. Vet Dermatol 28:71-e17|
|Landrock, Danilo; Milligan, Sherrelle; Martin, Gregory G et al. (2017) Effect of Fabp1/Scp-2/Scp-x Ablation on Whole Body and Hepatic Phenotype of Phytol-Fed Male Mice. Lipids 52:385-397|
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