Abstract

TheUniversityofKentucky(UK)CenterforClinicalandTranslationalScience(CCTS)TrainingProgramin ClinicalandTranslationalScience(UKTL1program)willprepareprofessionalandpredoctoralstudentsto assumeleadershiprolestodirectteamscienceacrosstheclinicalandtranslationalresearch(CTR)spectrum. Overthelastfiveyears,theUKTL1programhasleveragedUK?sCTRstrengthstoprovideamultidisciplinary andtransdirectionaltrainingprogramthatintegratestraineesacrossdiversefieldstoprovidearigorousand solidresearcheducationinCTR.Withthisapproach,wehaveachievedourgoalofincreasingthenumberof investigatorswhobridgethegapbetweenbasicscienceadvancesandtheirapplicationtoclinicalmedicine. Thishasbeenaccomplishedbyprovidingahighlycollaborativetrainingenvironmentthatincubatesscholars andmentorswithaninnovativeandnurturingstructuretodevelopresearchcompetenciesinateam-based environment.Thesuccessoftraineesinthefirstfundingcycleandthedevelopmentofaninnovativetraining processtoengageevengreaternumbersofstudentsinCTRarethefoundationforthefollowingSpecific Aims:1)toincreasethepipelineofinvestigatorsengagedinCTR;?2)totrainacrossthespectrumofCTR;?and 3)topreparescholarstoparticipateeffectivelyinteamscience.Tomeetouraims,weproposetoincreasethe numberofpredoctoralTL1studentssupportedeachyearandtoincludeanew12-monthintensiveCTR experiencetomeetanidentifiedneedamongprofessionalstudentsandmedicalprofessionalsinresidency. Wewillcontinuetosolicitapplicationsbroadlyacrosscampus,offernewexperientialtrainingincommunity researchinruralpopulationsinCentralAppalachia,anddevelopdoctoral-leveltraininginbiomedical informatics,takingadvantageoftherecentinfluxofleadershipandexpertiseinthisareaatUK.Finally,wewill providetraineeswiththelatestskillsetstoparticipateeffectivelyininterdisciplinaryandcollaborativeteam science.Theseinitiativeswillacceleratethecareerdevelopmentoffutureleadersofthebiomedicalresearch workforcewhocanaddresstoday?scomplexresearchchallengesandspearheadadvancesinhumanhealth.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Training Award (TL1)
Project #
5TL1TR001997-03
Application #
9511939
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Brazhnik, Olga
Project Start
2016-08-15
Project End
2020-05-31
Budget Start
2018-06-01
Budget End
2019-05-31
Support Year
3
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of Kentucky
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
939017877
City
Lexington
State
KY
Country
United States
Zip Code
40526

  Publications

Gupta, Vedant A; Leung, Steve W; Winkler, Michael A et al. (2018) Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans. J Vis Exp :
Brown, Christopher A; Jiang, Yang; Smith, Charles D et al. (2018) Age and Alzheimer's pathology disrupt default mode network functioning via alterations in white matter microstructure but not hyperintensities. Cortex 104:58-74
Bane, Maria; Brown, Megan; Angadi, Vrushali et al. (2018) Vocal function exercises for normal voice: With and without semi-occlusion. Int J Speech Lang Pathol :1-7
Stehouwer, Nathan; Okello, Emmy; Gupta, Vedant et al. (2018) Development and Validation of a Teaching Module for Echocardiographic Scoring of Rheumatic Mitral Stenosis. Glob Heart 13:105-111
Kline, Paul W; Burnham, Jeremy; Yonz, Michael et al. (2018) Hip external rotation strength predicts hop performance after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 26:1137-1144
Spear, Tyler J; Stromp, Tori A; Leung, Steve W et al. (2017) Influence of longitudinal position on the evolution of steady-state signal in cardiac cine balanced steady-state free precession imaging. Acta Radiol Open 6:2058460117729186
Bradford, Emily M; Ryu, Stacy H; Singh, Ajay Pal et al. (2017) Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease. J Immunol 199:1886-1897
Stephens, Dustin B; Young, April M; Havens, Jennifer R (2017) Healthcare contact and treatment uptake following hepatitis C virus screening and counseling among rural Appalachian people who use drugs. Int J Drug Policy 47:86-94
Johnson, Nathan F; Gold, Brian T; Brown, Christopher A et al. (2017) Endothelial Function Is Associated with White Matter Microstructure and Executive Function in Older Adults. Front Aging Neurosci 9:255
Brown, Christopher A; Johnson, Nathan F; Anderson-Mooney, Amelia J et al. (2017) Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease. Neuroimage Clin 13:106-115

Showing the most recent 10 out of 15 publications