Abstract

AIDS CLINICAL STUDIES GROUP INCLUDES: AIDS Research Treatment Program Effects of Anti-HIV-Therapy on HIV Load and on HIV-Medicated Modulation of Host Cell Gene Expression and Related Cytopathogenic Progress. Studies on the Specificity and Regulation of Anti-HIV Antibodies Using Human Monoclonal Antibody Technology. The Role and Characterization of Circulating Complexes in Patients with AIDS.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
3U01AI025902-05S2
Application #
3546914
Study Section
Special Emphasis Panel (SRC (03))
Project Start
1987-09-30
Project End
1993-12-31
Budget Start
1992-04-01
Budget End
1993-12-31
Support Year
5
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
St. Luke's Roosevelt Hosp Center (New York)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10025

  Publications

Shahabuddin, M; McKinley, G; Potash, M J et al. (1994) Modulation of cellular gene expression of HIV type 1 infection as determined by subtractive hybridization cloning: downregulation of thymosin beta 4 in vitro and in vivo. AIDS Res Hum Retroviruses 10:1525-9
Bodo, I; Vloka, J D; Cleveland, W L (1993) CD4 but not CD8 is comodulated with the T-cell antigen receptor (TCR) after activation of a CD4+ CD8+ human leukemia line with staphylococcal enterotoxin. Immunol Lett 37:53-62
Potash, M J; Bentsman, G; McKinley, G et al. (1992) A Tat antagonist inhibits HIV-1 induction in naturally infected and experimentally infected T cells. Biochem Biophys Res Commun 189:250-6
Volsky, B; Sakai, K; Reddy, M M et al. (1992) A system for the high efficiency replication of HIV-1 in neural cells and its application to anti-viral evaluation. Virology 186:303-8
Shahabuddin, M; Volsky, B; Kim, H et al. (1992) Regulated expression of human immunodeficiency virus type 1 in human glial cells: induction of dormant virus. Pathobiology 60:195-205
Volsky, D J; Li, G; Hamblet, N et al. (1992) Evaluation of multiple parameters of HIV-1 replication cycle in testing of AIDS drugs in vitro. Antiviral Res 17:335-47
Reddy, M M; Grieco, M H; McKinley, G F et al. (1992) Effect of foscarnet therapy on human immunodeficiency virus p24 antigen levels in AIDS patients with cytomegalovirus retinitis. J Infect Dis 166:607-10
Reddy, M M; Winger, E E; Hargrove, D et al. (1992) An improved method for monitoring efficacy of anti-retroviral therapy in HIV-infected individuals: a highly sensitive HIV p24 antigen assay. J Clin Lab Anal 6:125-9
Reddy, M M; Weissman, A M; Mazza, D S et al. (1992) Circulating elevated levels of soluble CD23, interleukin-4, and CD20+CD23+ lymphocytes in atopic subjects with elevated serum IgE concentrations. Ann Allergy 69:131-4
Zeira, M; Tosi, P F; Mouneimne, Y et al. (1991) Full-length CD4 electroinserted in the erythrocyte membrane as a long-lived inhibitor of infection by human immunodeficiency virus. Proc Natl Acad Sci U S A 88:4409-13

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