Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Tampa Bay Research Institute
Department
Type
DUNS #
City
Saint Petersburg
State
FL
Country
United States
Zip Code
33716
Sakagami, H; Konno, K; Kawazoe, Y et al. (1992) Multiple immunological functions of extracts from the cone of Japanese white pine, Pinus parviflora Sieb. et Zucc. Adv Exp Med Biol 319:331-5
Sakagami, H; Kawazoe, Y; Komatsu, N et al. (1991) Antitumor, antiviral and immunopotentiating activities of pine cone extracts: potential medicinal efficacy of natural and synthetic lignin-related materials (review). Anticancer Res 11:881-8
Harada, H; Sakagami, H; Nagata, K et al. (1991) Possible involvement of lignin structure in anti-influenza virus activity. Antiviral Res 15:41-9
Sakagami, H; Kawazoe, Y; Oh-hara, T et al. (1991) Stimulation of human peripheral blood polymorphonuclear cell iodination by lignin-related substances. J Leukoc Biol 49:277-82
Tamura, Y; Lai, P K; Bradley, W G et al. (1991) A soluble factor induced by an extract from Pinus parviflora Sieb et Zucc can inhibit the replication of human immunodeficiency virus in vitro. Proc Natl Acad Sci U S A 88:2249-53
Kikuchi, K; Sakagami, H; Fujinaga, S et al. (1991) Stimulation of mouse peritoneal macrophages by lignin-related substances. Anticancer Res 11:841-5
Lai, P K; Tamura, Y; Bradley, W G et al. (1991) Cytokine regulation of the human immunodeficiency virus (HIV). Int J Immunopharmacol 13 Suppl 1:55-61
Takayama, H; Bradley, G; Lai, P K et al. (1991) Inhibition of human immunodeficiency virus forward and reverse transcription by PC6, a natural product from cones of pine trees. AIDS Res Hum Retroviruses 7:349-57
Sakagami, H; Nagata, K; Ishihama, A et al. (1990) Anti-influenza virus activity of synthetically polymerized phenylpropenoids. Biochem Biophys Res Commun 172:1267-72
Sakagami, H; Kohno, S; Tanuma, S et al. (1990) Induction of cytotoxic factor in mice by lignified materials combined with OK-432 (Picibanil). In Vivo 4:371-5

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