Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01AI036467-03
Application #
2072778
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1994-09-15
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Gerloni, M; Miner, K T; Xiong, S et al. (1999) Activation of CD4 T cells by somatic transgenesis induces generalized immunity of uncommitted T cells and immunologic memory. J Immunol 162:3782-9
Gerloni, M; Lo, D; Ballou, W R et al. (1998) Immunological memory after somatic transgene immunization is positively affected by priming with GM-CSF and does not require bone marrow-derived dendritic cells. Eur J Immunol 28:1832-8
Gerloni, M; Xiong, S; Zanetti, M (1998) Durable immunity and immunologic memory to a parasite antigen induced by somatic transgene immunization. Vaccine 16:293-7
Gerloni, M; Lo, D; Zanetti, M (1998) DNA immunization in relB-deficient mice discloses a role for dendritic cells in IgM-->IgG1 switch in vivo. Eur J Immunol 28:516-24
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Xiong, S; Gerloni, M; Zanetti, M (1997) In vivo role of B lymphocytes in somatic transgene immunization. Proc Natl Acad Sci U S A 94:6352-7