Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01AI040319-01
Application #
2004949
Study Section
Special Emphasis Panel (ZAI1-VSG-A (60))
Project Start
1996-09-01
Project End
2000-05-31
Budget Start
1996-09-01
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Leav, Brett A; Mackay, Malanie R; Anyanwu, Akudo et al. (2002) Analysis of sequence diversity at the highly polymorphic Cpgp40/15 locus among Cryptosporidium isolates from human immunodeficiency virus-infected children in South Africa. Infect Immun 70:3881-90
Bonnin, A; Ojcius, D M; Souque, P et al. (2001) Characterization of a monoclonal antibody reacting with antigen-4 domain of gp900 in Cryptosporidium parvum invasive stages. Parasitol Res 87:589-92
Nelson, R G; Rosowsky, A (2001) Dicyclic and tricyclic diaminopyrimidine derivatives as potent inhibitors of Cryptosporidium parvum dihydrofolate reductase: structure-activity and structure-selectivity correlations. Antimicrob Agents Chemother 45:3293-303
Brophy, V H; Vasquez, J; Nelson, R G et al. (2000) Identification of Cryptosporidium parvum dihydrofolate reductase inhibitors by complementation in Saccharomyces cerevisiae. Antimicrob Agents Chemother 44:1019-28
Strong, W B; Nelson, R G (2000) Gene discovery in Cryptosporidium parvum: expressed sequence tags and genome survey sequences. Contrib Microbiol 6:92-115
Strong, W B; Nelson, R G (2000) Preliminary profile of the Cryptosporidium parvum genome: an expressed sequence tag and genome survey sequence analysis. Mol Biochem Parasitol 107:Jan-32
Strong, W B; Gut, J; Nelson, R G (2000) Cloning and sequence analysis of a highly polymorphic Cryptosporidium parvum gene encoding a 60-kilodalton glycoprotein and characterization of its 15- and 45-kilodalton zoite surface antigen products. Infect Immun 68:4117-34
Gut, J; Nelson, R G (1999) Cryptosporidium parvum: lectins mediate irreversible inhibition of sporozoite infectivity in vitro. J Eukaryot Microbiol 46:48S-49S
Gut, J; Nelson, R G (1999) Cryptosporidium parvum: synchronized excystation in vitro and evaluation of sporozoite infectivity with a new lectin-based assay. J Eukaryot Microbiol 46:56S-57S