The Bronx-Lebanon Hospital Center is applying for the Units for HIV/AIDS Clinical Trials Network grant(RFA-A1-05-002) as a Clinical Trials Unit Administrative Component (CTU) under the IMPAACT Leadership Network and in association with four clinical research sites located within a contiguous geographic region serving New York City: Bronx-Lebanon Hospital Center, St. Luke's-Roosevelt Hospital Center, Metropolitan Hospital Center, and the Montefiore Medical Center. Murli Purswani, MD, Principal Investigator for the Pediatric AIDS Clinical Trials Unit (PACTU) at Bronx-Lebanon, will serve as the CTU Principal Investigator. Activities will focus on four priority areas identified by DAIDS and supported by IMPAACT: (1) vaccine research and development;(2) translational research/drug development;(3) optimization of clinical management, including co-morbidities;and (4) prevention of mother-to-child transmission. As the Principal Investigator for the PACTU, currently funded by NIH, Dr. Purswani coordinates pediatric clinical trials research ongoing at Bronx-Lebanon Hospital Center and at each of the proposed clinical research sites. Together, the 4 research sites, as coordinated by Bronx-Lebanon as the proposed CTU, serve a broad-based, predominantly minority, impoverished population of infants, children, adolescents, and pregnant women n the Bronx and northern Manhattan, in New York City, an area of the United States disproportionately affected by the HIV/AIDS epidemic. ADMINISTRATIVE COMPONENT:

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01AI069413-04
Application #
7743464
Study Section
Special Emphasis Panel (ZAI1-DDS-A (M1))
Program Officer
Welsch, Sue A
Project Start
2007-02-01
Project End
2013-11-30
Budget Start
2009-12-01
Budget End
2010-11-30
Support Year
4
Fiscal Year
2010
Total Cost
$712,621
Indirect Cost
Name
Bronx-Lebanon Hosp Center (Bronx, NY)
Department
Type
DUNS #
073258493
City
New York
State
NY
Country
United States
Zip Code
10456