Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01AI073871-01
Application #
7251761
Study Section
Special Emphasis Panel (ZAI1-MP-I (M1))
Program Officer
Esch, Thomas R
Project Start
2006-09-15
Project End
2011-08-31
Budget Start
2006-09-15
Budget End
2007-08-31
Support Year
1
Fiscal Year
2006
Total Cost
$438,750
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655
Yang, Chaoxing; Jurczyk, Agata; diIorio, Philip et al. (2013) Salicylate prevents virus-induced type 1 diabetes in the BBDR rat. PLoS One 8:e78050
McNeer, N A; Schleifman, E B; Cuthbert, A et al. (2013) Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo. Gene Ther 20:658-69
Brehm, Michael A; Powers, Alvin C; Shultz, Leonard D et al. (2012) Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice. Cold Spring Harb Perspect Med 2:a007757
Bortell, Rita; Yang, Chaoxing (2012) The BB rat as a model of human type 1 diabetes. Methods Mol Biol 933:31-44
Brehm, Michael A; Racki, Waldemar J; Leif, Jean et al. (2012) Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r? null mice is enhanced by transgenic expression of membrane-bound human SCF. Blood 119:2778-88
Kincaid, Eleanor Z; Che, Jenny W; York, Ian et al. (2012) Mice completely lacking immunoproteasomes show major changes in antigen presentation. Nat Immunol 13:129-35
Liu, Zhijun; Cort, Laura; Eberwine, Ryan et al. (2012) Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: V?13 as a therapeutic target and biomarker. Diabetes 61:1160-8
Takagi, Shinsuke; Saito, Yoriko; Hijikata, Atsushi et al. (2012) Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation. Blood 119:2768-77
van Gils, Janine M; Derby, Merran C; Fernandes, Luciana R et al. (2012) The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques. Nat Immunol 13:136-43
Shultz, Leonard D; Brehm, Michael A; Bavari, Sina et al. (2011) Humanized mice as a preclinical tool for infectious disease and biomedical research. Ann N Y Acad Sci 1245:50-4

Showing the most recent 10 out of 20 publications