Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01CA048409-02
Application #
3549175
Study Section
(SRC)
Project Start
1988-09-15
Project End
1989-08-31
Budget Start
1989-08-01
Budget End
1989-08-31
Support Year
2
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Boston University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Qian, G S; Ross, R K; Yu, M C et al. (1994) A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China. Cancer Epidemiol Biomarkers Prev 3:3-10
Groopman, J D; Roebuck, B D; Kensler, T W (1994) Carcinogen-DNA and protein adducts as intermediate biomarkers for human chemoprotection trials. Adv Exp Med Biol 354:149-60
Wild, C P; Jansen, L A; Cova, L et al. (1993) Molecular dosimetry of aflatoxin exposure: contribution to understanding the multifactorial etiopathogenesis of primary hepatocellular carcinoma with particular reference to hepatitis B virus. Environ Health Perspect 99:115-22
Hollstein, M C; Wild, C P; Bleicher, F et al. (1993) p53 mutations and aflatoxin B1 exposure in hepatocellular carcinoma patients from Thailand. Int J Cancer 53:51-5
Groopman, J D; Wild, C P; Hasler, J et al. (1993) Molecular epidemiology of aflatoxin exposures: validation of aflatoxin-N7-guanine levels in urine as a biomarker in experimental rat models and humans. Environ Health Perspect 99:107-13
Wild, C P; Fortuin, M; Donato, F et al. (1993) Aflatoxin, liver enzymes, and hepatitis B virus infection in Gambian children. Cancer Epidemiol Biomarkers Prev 2:555-61
Sheabar, F Z; Groopman, J D; Qian, G S et al. (1993) Quantitative analysis of aflatoxin-albumin adducts. Carcinogenesis 14:1203-8
Groopman, J D; Hall, A J; Whittle, H et al. (1992) Molecular dosimetry of aflatoxin-N7-guanine in human urine obtained in The Gambia, West Africa. Cancer Epidemiol Biomarkers Prev 1:221-7
Allen, S J; Wild, C P; Wheeler, J G et al. (1992) Aflatoxin exposure, malaria and hepatitis B infection in rural Gambian children. Trans R Soc Trop Med Hyg 86:426-30
Wild, C P; Shrestha, S M; Anwar, W A et al. (1992) Field studies of aflatoxin exposure, metabolism and induction of genetic alterations in relation to HBV infection and hepatocellular carcinoma in The Gambia and Thailand. Toxicol Lett 64-65 Spec No:455-61

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