Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01CA048626-03
Application #
3813078
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Boston University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02118
vanderSpek, Johanna C; Sutherland, John A; Gill, Brian M et al. (2002) Structure function analysis of interleukin 7: requirement for an aromatic ring at position 143 of helix D. Cytokine 17:227-33
Gorgun, Gullu; van der Spek, Johanna; Cosenza, Larry et al. (2002) Altered biological activity associated with C-terminal modifications of IL-7. Cytokine 20:17-22
Sweeney, E B; Foss, F M; Murphy, J R et al. (1998) Interleukin 7 (IL-7) receptor-specific cell killing by DAB389 IL-7: a novel agent for the elimination of IL-7 receptor positive cells. Bioconjug Chem 9:201-7
Kelley, V R; Strom, T B (1995) A paradigm 1994: the allograft response. Blood Purif 13:199-205
Kelley, V R; Singer, G G (1993) The antigen presentation function of renal tubular epithelial cells. Exp Nephrol 1:102-11
vanderSpek, J C; Mindell, J A; Finkelstein, A et al. (1993) Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to J Biol Chem 268:12077-82
Maslinski, W; Remillard, B; Tsudo, M et al. (1993) Interleukin-2 receptor signal transduction: translocation of active serine-threonine kinase Raf-1 from IL-2 receptor into cytosol depends on IL-2-induced tyrosine kinase activation. Transplant Proc 25:109-10
Jevnikar, A M; Singer, G G; Coffman, T et al. (1993) Transgenic tubular cell expression of class II is insufficient to initiate immune renal injury. J Am Soc Nephrol 3:1972-7
Bloom, R D; Florquin, S; Singer, G G et al. (1993) Colony stimulating factor-1 in the induction of lupus nephritis. Kidney Int 43:1000-9
Singer, G G; Yokoyama, H; Bloom, R D et al. (1993) Stimulated renal tubular epithelial cells induce anergy in CD4+ T cells. Kidney Int 44:1030-5

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