Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01CA053801-05
Application #
2095509
Study Section
Special Emphasis Panel (SRC (72))
Project Start
1991-03-01
Project End
1999-06-30
Budget Start
1996-08-29
Budget End
1997-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
van Hattem, Willem Arnout; Langeveld, Danielle; de Leng, Wendy W J et al. (2011) Histologic variations in juvenile polyp phenotype correlate with genetic defect underlying juvenile polyposis. Am J Surg Pathol 35:530-6
Langeveld, Danielle; van Hattem, W Arnout; de Leng, Wendy W J et al. (2010) SMAD4 immunohistochemistry reflects genetic status in juvenile polyposis syndrome. Clin Cancer Res 16:4126-34
van Hattem, W Arnout; Brosens, Lodewijk A A; Marks, Susan Y et al. (2009) Increased cyclooxygenase-2 expression in juvenile polyposis syndrome. Clin Gastroenterol Hepatol 7:93-7
van Hattem, W A; Brosens, L A A; de Leng, W W J et al. (2008) Large genomic deletions of SMAD4, BMPR1A and PTEN in juvenile polyposis. Gut 57:623-7
Brosens, Lodewijk A A; Keller, Josbert J; Pohjola, Leena et al. (2008) Increased expression of cytoplasmic HuR in familial adenomatous polyposis. Cancer Biol Ther 7:424-7
Brosens, Lodewijk A A; van Hattem, Arnout; Hylind, Linda M et al. (2007) Risk of colorectal cancer in juvenile polyposis. Gut 56:965-7
de Leng, W W J; Jansen, M; Carvalho, R et al. (2007) Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates. Clin Genet 72:568-73
Cruz-Correa, Marcia; Shoskes, Daniel A; Sanchez, Patricia et al. (2006) Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis. Clin Gastroenterol Hepatol 4:1035-8
Hisamuddin, Irfan M; Wehbi, Mohammad A; Schmotzer, Brian et al. (2005) Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis. Cancer Epidemiol Biomarkers Prev 14:2366-9
Giardiello, Francis M; Hylind, Linda M; Trimbath, Jill D et al. (2005) Oral contraceptives and polyp regression in familial adenomatous polyposis. Gastroenterology 128:1077-80

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