An ongoing 17 year follow-up study of 120,000 U.S. nurses has produced important information on causes and preventives of cancer and cardiovascular disease in white women (some 100 papers to date), and other large follow-up studies of white women have been started more recently. There are no comparable studies in black women, who bear a greater burden of illness and mortality. [Results on the etiology of disease in white women may not be generalizable to black women because of genetic differences, differences in risk factors, or other reasons.] We propose to conduct a large prospective follow-up study of black women to provide informative data on risk factors for cancer, cardiovascular disease, and other major illnesses, with an emphasis on the health effects of obesity. Other factors to be assessed include cigarette smoking, physical activity, alcohol use, die, exogenous estrogen use, and reproductive factors. We will enroll, by means of a mailed questionnaire, 50,000 black women up to age 69 years who are members of the National Education Association, employees of the federal government, nurses, or friends of these women. These women were chosen because of evidence that they can provide reliable health information and be followed with few losses. Pilot studies carried out with the assistance of both the National Education Association and the U.S. Office of Personnel Management have demonstrated the feasibility of the project. An Advisory Board of black women knowledgeable about health problems in the black community has participated and will continue to give advice and guidance; expert consultants on black women's health will have important input to the study. The initial questionnaire will collect information on exposures and covariates of interest. Follow-up mail questionnaires at 2-year intervals will update information and ascertain incident cases of cancer, cardiovascular disease, and other major illnesses; diagnoses will be documented by review of medical records and other documents. Deaths will be ascertained from families and friends and through the National Death Index. Interim mailings will be made to sustain the interest of the participants and to inform them of study results. This study will provide needed information on the etiology of disease in black women, a heretofore neglected group in health studies. [The etiologic results will generally be applicable to millions of U.S. black women, including poor women,] and the results will be useful in preventive programs focused on reducing morbidity and mortality.
| Cozier, Yvette C; Albert, Michelle A; Castro-Webb, Nelsy et al. (2016) Neighborhood Socioeconomic Status in Relation to Serum Biomarkers in the Black Women's Health Study. J Urban Health 93:279-91 |
| Lillioja, Stephen; Neal, Andrew L; Tapsell, Linda et al. (2013) Whole grains, type 2 diabetes, coronary heart disease, and hypertension: links to the aleurone preferred over indigestible fiber. Biofactors 39:242-58 |
| Tukey, M H; Berman, J S; Boggs, D A et al. (2013) ??Mortality among African American women with sarcoidosis: data from the Black Women's Health Study. Sarcoidosis Vasc Diffuse Lung Dis 30:128-33 |
| Wise, Lauren A; Radin, Rose G; Palmer, Julie R et al. (2012) Association of intrauterine and early life factors with uterine leiomyomata in black women. Ann Epidemiol 22:847-54 |
| Radin, R G; Rosenberg, L; Palmer, J R et al. (2012) Hypertension and risk of uterine leiomyomata in US black women. Hum Reprod 27:1504-9 |
| Coogan, Patricia F; White, Laura F; Evans, Stephen R et al. (2012) The influence of neighborhood socioeconomic status and walkability on TV viewing time. J Phys Act Health 9:1074-9 |
| Wise, Lauren A; Rosenberg, Lynn; Radin, Rose G et al. (2011) A prospective study of diabetes, lifestyle factors, and glaucoma among African-American women. Ann Epidemiol 21:430-9 |
| Makambi, Kepher H; Agurs-Collins, Tanya; Bright-Gbebry, Mireille et al. (2011) Dietary patterns and the risk of colorectal adenomas: the Black Women's Health Study. Cancer Epidemiol Biomarkers Prev 20:818-25 |
| Boggs, Deborah A; Rosenberg, Lynn; Ruiz-Narvaez, Edward A et al. (2010) Coffee, tea, and alcohol intake in relation to risk of type 2 diabetes in African American women. Am J Clin Nutr 92:960-6 |
| Wise, Lauren A; Rosenberg, Lynn; Palmer, Julie R et al. (2008) Anthropometric risk factors for colorectal polyps in African-American women. Obesity (Silver Spring) 16:859-68 |
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