This application responds to the need for Operations/Data Management and Statistical Centers for RFA 92-CA-02 that will become part of the on-going Radiological Diagnostic Oncology Group (RDOG). The proposed centers will continue to be based at the American College of Radiology and Harvard Medical School respectively. This application requests continued support for several tasks. Key ones include the following: 1) to support investigators in the design, development and implementation of new protocols; 2) to work with them in the design, development and implementation of data collection mechanisms; 3) to continually monitor and verify image quality, protocol compliance and data completeness; 4) to design and perform statistical analyses of the data and to generate relevant reports; and 5) to address methodologic issues arising in the design and analysis of collaborative imaging studies. We will also participate in the preparation of abstracts and manuscripts based on protocol findings. With the support of these centers and the institutions participating in RFA 92-CA-02, we will extend our research to two important classes of patients, children and women.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01CA059404-01
Application #
3550054
Study Section
Special Emphasis Panel (SRC (58))
Project Start
1992-09-30
Project End
1995-09-29
Budget Start
1992-09-30
Budget End
1993-09-29
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
American College of Radiology
Department
Type
DUNS #
City
Philadelphia
State
VA
Country
United States
Zip Code
Toledano, A Y; Gatsonis, C (1999) Generalized estimating equations for ordinal categorical data: arbitrary patterns of missing responses and missingness in a key covariate. Biometrics 55:488-96
Toledano, A Y; Gatsonis, C (1996) Ordinal regression methodology for ROC curves derived from correlated data. Stat Med 15:1807-26
Toledano, A; Gatsonis, C A (1995) Regression analysis of correlated receiver operating characteristic data. Acad Radiol 2 Suppl 1:S30-6;discussion S61-4, S70-1 p
Rutter, C M; Gatsonis, C A (1995) Regression methods for meta-analysis of diagnostic test data. Acad Radiol 2 Suppl 1:S48-56;discussion S65-7, S70-1