Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01CA061398-04
Application #
2102138
Study Section
Special Emphasis Panel (SRC (59))
Project Start
1993-09-01
Project End
1997-09-04
Budget Start
1996-07-01
Budget End
1997-09-04
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Connecticut
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Farmington
State
CT
Country
United States
Zip Code
06030
Chhabra, Arvind; Mehrotra, Shikhar; Chakraborty, Nitya G et al. (2006) Activation-induced cell death of human melanoma specific cytotoxic T lymphocytes is mediated by apoptosis-inducing factor. Eur J Immunol 36:3167-74
Chakraborty, Nitya G; Chattopadhyay, Subhasis; Mehrotra, Shikhar et al. (2004) Regulatory T-cell response and tumor vaccine-induced cytotoxic T lymphocytes in human melanoma. Hum Immunol 65:794-802
Mehrotra, Shikhar; Chhabra, Arvind; Chakraborty, Abolokita et al. (2004) Antigen presentation by MART-1 adenovirus-transduced interleukin-10-polarized human monocyte-derived dendritic cells. Immunology 113:472-81
Mehrotra, Shikhar; Chhabra, Arvind; Chattopadhyay, Subhasis et al. (2004) Rescuing melanoma epitope-specific cytolytic T lymphocytes from activation-induced cell death, by SP600125, an inhibitor of JNK: implications in cancer immunotherapy. J Immunol 173:6017-24
Mehrotra, Shikhar; Stevens, Robert; Zengou, Ryan et al. (2003) Regulation of melanoma epitope-specific cytolytic T lymphocyte response by immature and activated dendritic cells, in vitro. Cancer Res 63:5607-14
Chakraborty, A; Li, L; Chakraborty, N G et al. (2000) Stimulatory and inhibitory differentiation of human myeloid dendritic cells. Clin Immunol 94:88-98
Chakraborty, N G; Li, L; Sporn, J R et al. (1999) Emergence of regulatory CD4+ T cell response to repetitive stimulation with antigen-presenting cells in vitro: implications in designing antigen-presenting cell-based tumor vaccines. J Immunol 162:5576-83
Chakraborty, A; Li, L; Chakraborty, N G et al. (1999) Stimulatory and inhibitory maturation of human macrophage-derived dendritic cells. Pathobiology 67:282-6
Chakraborty, N G; Sporn, J R; Tortora, A F et al. (1998) Immunization with a tumor-cell-lysate-loaded autologous-antigen-presenting-cell-based vaccine in melanoma. Cancer Immunol Immunother 47:58-64
Perez-Diez, A; Butterfield, L H; Li, L et al. (1998) Generation of CD8+ and CD4+ T-cell response to dendritic cells genetically engineered to express the MART-1/Melan-A gene. Cancer Res 58:5305-9

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