Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01CA067941-01
Application #
2111754
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1996-03-15
Project End
1999-02-28
Budget Start
1996-03-15
Budget End
1997-02-28
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Helsinki
Department
Type
DUNS #
City
Helsinki
State
Country
Finland
Zip Code
00014
Le, Dung T; Durham, Jennifer N; Smith, Kellie N et al. (2017) Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade. Science 357:409-413
Haraldsdottir, Sigurdis; Hampel, Heather; Wu, Christina et al. (2016) Patients with colorectal cancer associated with Lynch syndrome and MLH1 promoter hypermethylation have similar prognoses. Genet Med 18:863-8
Le, Dung T; Uram, Jennifer N; Wang, Hao et al. (2015) PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. N Engl J Med 372:2509-20
Pasche, Boris; Pennison, Michael J; Jimenez, Hugo et al. (2014) TGFBR1 and cancer susceptibility. Trans Am Clin Climatol Assoc 125:300-12
Haraldsdottir, Sigurdis; Hampel, Heather; Tomsic, Jerneja et al. (2014) Colon and endometrial cancers with mismatch repair deficiency can arise from somatic, rather than germline, mutations. Gastroenterology 147:1308-1316.e1
Hampel, Heather; de la Chapelle, Albert (2013) How do we approach the goal of identifying everybody with Lynch syndrome? Fam Cancer 12:313-7
Tomsic, J; Senter, L; Liyanarachchi, S et al. (2013) Recurrent and founder mutations in the PMS2 gene. Clin Genet 83:238-43
Tomsic, Jerneja; Liyanarachchi, Sandya; Hampel, Heather et al. (2012) An American founder mutation in MLH1. Int J Cancer 130:2088-95
Tuupanen, Sari; Yan, Jian; Turunen, Mikko et al. (2012) Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583. Cancer Genet 205:25-33
Win, Aung Ko; Walters, Rhiannon J; Buchanan, Daniel D et al. (2012) Cancer risks for relatives of patients with serrated polyposis. Am J Gastroenterol 107:770-8

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