We will accrue all patients with newly diagnosed lung or colon cancer receiving their care in one of five geographically diverse sites in the Cancer Research Network, an NCI-funded research consortium of HMOs. Automated data for all patients (2,058 patients with lung cancer over the two year enrollment period, and 1,732 patients with colon cancer over the two year enrollment period) will be supplemented with data obtained from complete medical record review and patient surveys for a sample of 1,424 patients with newly diagnosed lung cancer and 1,222 patients with newly diagnosed colon cancer. We will oversample African-Americans, Asians and Pacific Islanders, as well as Medicaid recipients. In addition, we will assemble an inception cohort of patients with newly diagnosed metastatic recurrences of colorectal cancer during the two-year enrollment period (projected at approximately 300 patients) for comprehensive data collection. We propose to lead analyses of CanCORS-wide core data in order to (1) examine the effect of race and ethnicity on patterns of care, treatment choice, quality of life, symptom control, and satisfaction; (2) characterize the types of providers seen by patients and examine the associations between provider characteristics/attitudes and patterns of care and outcomes; (3) evaluate the relationship between the structure/function of cancer care in the health care delivery systems of participating patients and patient outcomes, including health status, patient satisfaction, and cost; and (4) generate estimates of utility weights and time- and out-of-pocket costs that are disease- and treatment-specific for use in future cost-effectiveness analyses. Finally, in a Special Research Study we will aggregate cost data for CRN CanCORS subjects in order to (1) determine cancer-attributable phase-specific and lifetime costs of care for colorectal and lung cancer; (2) determine the proportion of total cancer-attributable costs that are spent on initial therapy versus second- and third line therapies for each cancer, stratified by stage at diagnosis; and (3) determine the relationship between type of initial therapy and the subsequent lifetime cancer-attributable costs of care.
| Mehta, Anish J; Stock, Shannon; Gray, Stacy W et al. (2018) Factors contributing to disparities in mortality among patients with non-small-cell lung cancer. Cancer Med 7:5832-5842 |
| Roydhouse, Jessica K; Gutman, Roee; Keating, Nancy L et al. (2018) The Association of Proxy Care Engagement with Proxy Reports of Patient Experience and Quality of Life. Health Serv Res 53:3809-3824 |
| Litzelman, Kristin; Kent, Erin E; Rowland, Julia H (2018) Interrelationships Between Health Behaviors and Coping Strategies Among Informal Caregivers of Cancer Survivors. Health Educ Behav 45:90-100 |
| Roydhouse, Jessica K; Gutman, Roee; Keating, Nancy L et al. (2018) Proxy and patient reports of health-related quality of life in a national cancer survey. Health Qual Life Outcomes 16:6 |
| Duberstein, Paul R; Chen, Michael; Chapman, Benjamin P et al. (2018) Fatalism and educational disparities in beliefs about the curability of advanced cancer. Patient Educ Couns 101:113-118 |
| Keating, Nancy L; Huskamp, Haiden A; Kouri, Elena et al. (2018) Factors Contributing To Geographic Variation In End-Of-Life Expenditures For Cancer Patients. Health Aff (Millwood) 37:1136-1143 |
| Roydhouse, Jessica K; Gutman, Roee; Keating, Nancy L et al. (2018) Differences between Proxy and Patient Assessments of Cancer Care Experiences and Quality Ratings. Health Serv Res 53:919-943 |
| Hassett, Michael J; Uno, Hajime; Cronin, Angel M et al. (2017) Survival after recurrence of stage I-III breast, colorectal, or lung cancer. Cancer Epidemiol 49:186-194 |
| Mollica, Michelle A; Litzelman, Kristin; Rowland, Julia H et al. (2017) The role of medical/nursing skills training in caregiver confidence and burden: A CanCORS study. Cancer 123:4481-4487 |
| Kumar, Pallavi; Wright, Alexi A; Hatfield, Laura A et al. (2017) Family Perspectives on Hospice Care Experiences of Patients with Cancer. J Clin Oncol 35:432-439 |
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