Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01CA168930-01
Application #
8561416
Study Section
Special Emphasis Panel (ZCA1-SRLB-4 (M1))
Project Start
2012-08-23
Project End
2017-06-30
Budget Start
2012-08-23
Budget End
2013-06-30
Support Year
1
Fiscal Year
2012
Total Cost
$427,388
Indirect Cost
$141,737
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Sun, Xiaodong; Ju, Tongzhong; Cummings, Richard D (2018) Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers. BMC Cancer 18:827
Kudelka, Matthew R; Nairn, Alison V; Sardar, Mohammed Y et al. (2018) Isotopic labeling with cellular O-glycome reporter/amplification (ICORA) for comparative O-glycomics of cultured cells. Glycobiology 28:214-222
Kudelka, Matthew R; Hinrichs, Benjamin H; Darby, Trevor et al. (2016) Cosmc is an X-linked inflammatory bowel disease risk gene that spatially regulates gut microbiota and contributes to sex-specific risk. Proc Natl Acad Sci U S A 113:14787-14792
Kudelka, Matthew R; Antonopoulos, Aristotelis; Wang, Yingchun et al. (2016) Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells. Nat Methods 13:81-6
Stowell, Sean R; Ju, Tongzhong; Cummings, Richard D (2015) Protein glycosylation in cancer. Annu Rev Pathol 10:473-510
Kudelka, Matthew R; Ju, Tongzhong; Heimburg-Molinaro, Jamie et al. (2015) Simple sugars to complex disease--mucin-type O-glycans in cancer. Adv Cancer Res 126:53-135
Ju, Tongzhong; Aryal, Rajindra P; Kudelka, Matthew R et al. (2014) The Cosmc connection to the Tn antigen in cancer. Cancer Biomark 14:63-81
Cummings, Richard D; Pierce, J Michael (2014) The challenge and promise of glycomics. Chem Biol 21:1-15
Ju, Tongzhong; Wang, Yingchun; Aryal, Rajindra P et al. (2013) Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers. Proteomics Clin Appl 7:618-31
Brazil, Jennifer C; Liu, Renpeng; Sumagin, Ronen et al. (2013) ?3/4 Fucosyltransferase 3-dependent synthesis of Sialyl Lewis A on CD44 variant containing exon 6 mediates polymorphonuclear leukocyte detachment from intestinal epithelium during transepithelial migration. J Immunol 191:4804-17