Cocaine abuse is a major public health problem with enormous personal and societal costs. The need for treatments that are both effective and cost-effective is clear and compelling. The present proposal seeks to evaluate the relative effectiveness and cost-effectiveness of three, promising psychosocial treatments for cocaine abuse: (1) Supportive-Expressive psychotherapy plus drug counseling (2) Cognitive-Behavioral psychotherapy plus drug counseling, and (3) Drug Counseling alone provided by two counselors. At each of four Collaborative Treatment Sites, 90 medication-free, cocaine-dependent outpatients, of varying levels of psychiatric severity, with and without antisocial personality disorder, will be randomly assigned to one of the three treatment conditions and followed prospectively for two years. Treatment outcome will be evaluated at regular intervals, using a comprehensive and multifaceted assessment battery. Concurrently, data on law enforcement, employment, family burden, and treatment costs will be obtained. These will be combined with the treatment efficacy data and with data on outcome utilities representing a variety of perspectives. The cost-effectiveness and cost-utility of the three treatment then will be compared..
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| Stulz, Niklaus; Gallop, Robert; Lutz, Wolfgang et al. (2010) Examining differential effects of psychosocial treatments for cocaine dependence: an application of latent trajectory analyses. Drug Alcohol Depend 106:164-72 |
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| Crits-Christoph, Paul; Gibbons, Mary Beth Connolly; Barber, Jacques P et al. (2003) Mediators of outcome of psychosocial treatments for cocaine dependence. J Consult Clin Psychol 71:918-25 |
| Woody, George E; Gallop, Robert; Luborsky, Lester et al. (2003) HIV risk reduction in the National Institute on Drug Abuse Cocaine Collaborative Treatment Study. J Acquir Immune Defic Syndr 33:82-7 |
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| Crits-Christoph, P; Siqueland, L; McCalmont, E et al. (2001) Impact of psychosocial treatments on associated problems of cocaine-dependent patients. J Consult Clin Psychol 69:825-30 |
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