Principal Investigator/Program Director (Last, first, middle): Miller, Josef, M. RESEARCH &RELATED Other Project Information 1. * Are Human Subjects Involved? l Yes m No 1.a. If YES to Human Subjects Is the IRB review Pending? l Yes m No IRB Approval Date: Exemption Number: 1 2 3 4 5 6 Human Subject Assurance Number 00004969 2. * Are Vertebrate Animals Used? m Yes l No 2.a. If YES to Vertebrate Animals Is the IACUC review Pending? m Yes m No IACUC Approval Date: Animal Welfare Assurance Number 3. * Is proprietary/privileged information m Yes l No included in the application? 4.a.* Does this project have an actual or potential impact on m Yes l No the environment? 4.b. If yes, please explain: 4.c. If this project has an actual or potential impact on the environment, has an exemption been authorized or an environmental assessment (EA) or environmental impact statement (EIS) been performed? m Yes m No 4.d. If yes, please explain: 5.a.* Does this project involve activities outside the U.S. or l Yes m No partnership with International Collaborators? 5.b. If yes, identify countries: Spain, Sweden 5.c. Optional Explanation: Please See Other Attachments 6. * Project Summary/Abstract 8691-Abstract.pdf Mime Type: application/pdf 7. * Project Narrative 1485-Narrative.pdf Mime Type: application/pdf 8. Bibliography &References Cited 0013-Bibliography.pdf Mime Type: application/pdf 9. Facilities &Other Resources 9467-FacilitiesResources.pdf Mime Type: application/pdf 10. Equipment 3211-Equipment.pdf Mime Type: application/pdf 11. Other Attachments 9617-Scientific_Environment,_CollaboratMioinmse_PTuyrpeE:dagpep.lpicdaftion/pdf Tracking Number: Other Information Page 6 OMB Number: 4040-0001 Expiration Date: 04/30/2008

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project--Cooperative Agreements (U01)
Project #
3U01DC008423-02S1
Application #
7922970
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Program Officer
Hughes, Gordon B
Project Start
2009-09-17
Project End
2012-08-31
Budget Start
2009-09-17
Budget End
2012-08-31
Support Year
2
Fiscal Year
2009
Total Cost
$297,519
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Le Prell, C G; Fulbright, A; Spankovich, C et al. (2016) Dietary supplement comprised of ?-carotene, vitamin C, vitamin E, and magnesium: failure to prevent music-induced temporary threshold shift. Audiol Neurotol Extra 6:20-39
Spankovich, C; Le Prell, C G (2014) Associations between dietary quality, noise, and hearing: data from the National Health and Nutrition Examination Survey, 1999-2002. Int J Audiol 53:796-809
Le Prell, Colleen G; Spankovich, Christopher; LobariƱas, Edward et al. (2013) Extended high-frequency thresholds in college students: effects of music player use and other recreational noise. J Am Acad Audiol 24:725-39
Spankovich, C; Le Prell, C G (2013) Healthy diets, healthy hearing: National Health and Nutrition Examination Survey, 1999-2002. Int J Audiol 52:369-76
Le Prell, Colleen G; Dell, Shawna; Hensley, Brittany et al. (2012) Digital music exposure reliably induces temporary threshold shift in normal-hearing human subjects. Ear Hear 33:e44-58
Watanabe, Reiko; Morell, Maria H; Miller, Josef M et al. (2012) Nestin-expressing cells in the developing, mature and noise-exposed cochlear epithelium. Mol Cell Neurosci 49:104-9
Le Prell, C G; Johnson, A C; Lindblad, A C et al. (2011) Increased vitamin plasma levels in Swedish military personnel treated with nutrients prior to automatic weapon training. Noise Health 13:432-43
Le Prell, C G; Yang, Q; Harris, J G (2011) Modification of digital music files for use in human temporary threshold shift studies. J Acoust Soc Am 130:EL142-6
Le Prell, C G; Hensley, B N; Campbell, K C M et al. (2011) Evidence of hearing loss in a 'normally-hearing' college-student population. Int J Audiol 50 Suppl 1:S21-31