Overall Goal -To develop a model for the prevention of Fetal Alcohol Syndrome and Alcohol Related Birth Defects that can be applied in different areas of South Africa. Stage I - Formative -The primary objective for Stage 1 is to fully understand the current patterns, norms, and consequences of alcohol consumption, of women of child bearing age, and the current alcohol related services. Stage II - Interventions -Develop and implement a detailed intervention program and monitoring plan based on the findings of Stage I, to include interventions that are specific to the individual, the group, and the general community level. Stage III - Evaluation- Evaluate each of the components of the intervention program, and assess the extent to which they could be sustained on a larger scale, in an integrated model. The study will use a participatory action research approach, with a community advisory board established in the two research sites. The sites: an urban area of Pretoria in the Tshwane Municipality, and a rural farming area of the Western Cape. A KAP survey (750 households), services audit, FAS family case studies, and mapping of liquor outlets will provide information on which to create a conceptual framework and to base a multi-level intervention program aiming to reduce risky drinking and promote family planning, especially by childbearing age women. The interventions will be executed in collaboration with existing services, using a health promotion approach. A randomized controlled trial will be used to assess the efficacy of augmented counseling over regular counseling. The support groups and community awareness campaign will assess to what extent the interventions have shifted the local awareness regarding the planning of pregnancy and the levels of risky drinking. Fetal Alcohol Syndrome and other alcohol related birth defects have been found to be at high levels in some rural and urban areas in South Africa, and there is a generally high level of risky drinking across all population groups of women in childbearing age. The health and social services are overwhelmed with the HIV/AIDS epidemic, and to date no prevention study has been done to investigate appropriate and sustainable strategies to prevent women of childbearing age from drinking in pregnancy, and to enable them to better plan their pregnancies. ? ? ?

Agency
National Institute of Health (NIH)
Institute
Centers for Disease Control and Prevention (NCBDD)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01DD000044-01
Application #
7092758
Study Section
Special Emphasis Panel (ZCD1-PXJ (01))
Program Officer
Irannejad, Nassi
Project Start
2005-09-15
Project End
2008-09-14
Budget Start
2005-09-15
Budget End
2006-09-14
Support Year
1
Fiscal Year
2005
Total Cost
$237,076
Indirect Cost
Name
University of Pretoria
Department
Type
DUNS #
653373162
City
Pretoria
State
Country
South Africa
Zip Code
0002
Muhwava, Lorrein Shamiso; Morojele, Neo; London, Leslie (2016) Psychosocial factors associated with early initiation and frequency of antenatal care (ANC) visits in a rural and urban setting in South Africa: a cross-sectional survey. BMC Pregnancy Childbirth 16:18
Rendall-Mkosi, Kirstie; Morojele, Neo; London, Leslie et al. (2013) A randomized controlled trial of motivational interviewing to prevent risk for an alcohol-exposed pregnancy in the Western Cape, South Africa. Addiction 108:725-32
Peer, N; Morojele, N; London, L (2013) Factors associated with contraceptive use in a rural area in Western Cape Province. S Afr Med J 103:406-12
Mwansa-Kambafwile, Judith; Rendall-Mkosi, Kirstie; Jacobs, Rosemary et al. (2011) Evaluation of a service provider short course for prevention of fetal alcohol syndrome. J Stud Alcohol Drugs 72:530-5
Morojele, Neo K; London, Leslie; Olorunju, Steve A et al. (2010) Predictors of risk of alcohol-exposed pregnancies among women in an urban and a rural area of South Africa. Soc Sci Med 70:534-42
Ojo, Oluwayemisi A; Louwagie, Goedele; Morojele, Neo et al. (2010) Factors associated with female high-risk drinking in a rural and an urban South African site. S Afr Med J 100:180-2