Abstract

The Loyola Female Pelvic Medicine team proposes to participate in the Interstitial Cystitis/Chronic Pelvic Pain (IC/CPP) Clinical Trials Network in order to advance the understanding of the clinical care of women with these complex disorders. Our multidisciplinary team has the clinical volume and proven ability to participate in development of cooperative studies and to recruit to finally approved protocols. As a referral center for IC/CPP in the Chicago area, we believe our participation will benefit the network by bringing a large patient base and a long clinical experience to the group, and will benefit our patients by making state-of-the-art treatments available to them. As requested in the RFA, we offer a concept protocol which studies the use of botulinum toxin injection into either detrusor or pelvic floor musculature, for the treatment of IC/CPP. The Loyola team: Understands the significance of this important treatment network, Can recruit and retain patients of racial, economic and ethnic diversity, Has experienced investigators including physicians, nurses, physical therapist and urodynamic technicians, Has a current clinical practice which offers surgical, pharmacological and behavioral treatment for IC/CPP, Can ensure data management and transmission, and Looks forward to cooperation with the other treatment centers in order to maximize the benefits of this treatment network for our patients.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01DK065214-02
Application #
6794193
Study Section
Special Emphasis Panel (ZDK1-GRB-1 (M2))
Program Officer
Kusek, John W
Project Start
2003-09-01
Project End
2008-02-28
Budget Start
2004-02-29
Budget End
2005-02-28
Support Year
2
Fiscal Year
2004
Total Cost
$250,000
Indirect Cost

  Institution

Name
Loyola University Chicago
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
791277940
City
Maywood
State
IL
Country
United States
Zip Code
60153

  Publications

FitzGerald, M P; Payne, C K; Lukacz, E S et al. (2012) Randomized multicenter clinical trial of myofascial physical therapy in women with interstitial cystitis/painful bladder syndrome and pelvic floor tenderness. J Urol 187:2113-8
Yang, Claire C; Burks, David A; Propert, Kathleen J et al. (2011) Early termination of a trial of mycophenolate mofetil for treatment of interstitial cystitis/painful bladder syndrome: lessons learned. J Urol 185:901-6
Foster Jr, Harris E; Hanno, Philip M; Nickel, J Curtis et al. (2010) Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome. J Urol 183:1853-8
Hatchett, Lena; Fitzgerald, Mary Pat; Potts, Jeannette et al. (2009) Life impact of urologic pain syndromes. J Health Psychol 14:741-50