Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project--Cooperative Agreements (U01)
Project #
1U01DK078123-01
Application #
7250804
Study Section
Special Emphasis Panel (ZAI1-MP-I (M1))
Program Officer
Akolkar, Beena
Project Start
2006-09-20
Project End
2011-07-31
Budget Start
2006-09-20
Budget End
2007-07-31
Support Year
1
Fiscal Year
2006
Total Cost
$312,433
Indirect Cost
Name
Stanford University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Creusot, RĂ©mi J; Giannoukakis, Nick; Trucco, Massimo et al. (2014) It's time to bring dendritic cell therapy to type 1 diabetes. Diabetes 63:20-30
Yip, Linda; Fathman, C Garrison (2014) Type 1 diabetes in mice and men: gene expression profiling to investigate disease pathogenesis. Immunol Res 58:340-50
Kurnellas, Michael P; Schartner, Jill M; Fathman, C Garrison et al. (2014) Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease. J Exp Med 211:1847-56
Yip, Linda; Taylor, Cariel; Whiting, Chan C et al. (2013) Diminished adenosine A1 receptor expression in pancreatic ?-cells may contribute to the pathology of type 1 diabetes. Diabetes 62:4208-19
Yip, Linda; Creusot, Remi J; Pager, Cara T et al. (2013) Reduced DEAF1 function during type 1 diabetes inhibits translation in lymph node stromal cells by suppressing Eif4g3. J Mol Cell Biol 5:99-110
Kurnellas, Michael P; Adams, Chris M; Sobel, Raymond A et al. (2013) Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation. Sci Transl Med 5:179ra42
Rothbard, Jonathan B; Kurnellas, Michael P; Brownell, Sara et al. (2012) Therapeutic effects of systemic administration of chaperone ?B-crystallin associated with binding proinflammatory plasma proteins. J Biol Chem 287:9708-21
Levin, Aron M; Bates, Darren L; Ring, Aaron M et al. (2012) Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'. Nature 484:529-33
Junttila, Ilkka S; Creusot, Remi J; Moraga, Ignacio et al. (2012) Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines. Nat Chem Biol 8:990-8
Kurnellas, Michael P; Brownell, Sara E; Su, Leon et al. (2012) Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis. J Biol Chem 287:36423-34

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