In response to the Centers for Disease Control and Prevention (CDC) RFA-DP-05-071, Louisiana Tumor Registry (LTR) submits this application to conduct a patterns of care study (POC) for the two priority cancers: female breast and prostate. The long term goal of this study is to further develop the capacity of LTR to engage in advanced cancer surveillance activities that will contribute to improving care that cancer patients receive in Louisiana and in the nation. The objectives of this study are to: (1) determine the proportion of patients who received the state-of-art treatment for stages l-lll female breast cancer and describe the treatment patterns for all stages of prostate cancer; (2) determine how the tumor, patient, provider, and health system characteristics are associated with different cancer treatment for breast cancer prostate cancers; (3) assess the completeness and quality of the stage and first course of treatment data for these two cancers in LTR routine dataset. All patients aged 20 and older who had no prior cancer except non- melanoma skin cancer and were diagnosed microscopically with one of the study cancers in the two most current diagnosis years available, as determined by the CDC's Steering Committee, will be eligible for this study. We propose to randomly select 480 white and 480 black eligible cases for each of the study cancers and for each year of the 2003 and 2004. All eligible Asians/Pacific Islanders, American Indians/Alaska Natives and Hispanics will be included. We are expected to have a total of 1,000 cases for each of the study years and for each of the study cancer sites. We will collaborate with the investigators from CDC and other participating states to develop the study protocol, manual and data entry instruments, which will be based on the previous CDC's CONCORD/POC study. Data Collection will be carried out by the abstractors from LTR central offices, regional and hospital registries. Hospital records (inpatient and outpatient) of the sampled cases will be reviewed to collect information required by this study. Special effort will be made to verify treatment information with treating physicians unless the treatment information is from unified hospital records. The inforamtion collected for this study will assist health care providers as they seek to provide the highest quality of care for their patients andwill help with interventions to improve quality of care for all cancer patients.

Agency
National Institute of Health (NIH)
Institute
National Center for Chronic Disease Prev and Health Promo (NCCDPHP)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01DP000253-03
Application #
7281664
Study Section
Special Emphasis Panel (ZDP1-GXC (01))
Program Officer
Colley Gilbert, Brenda J
Project Start
2005-09-30
Project End
2009-09-29
Budget Start
2007-09-30
Budget End
2009-09-29
Support Year
3
Fiscal Year
2007
Total Cost
$322,751
Indirect Cost
Name
Louisiana State Univ Hsc New Orleans
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
Satkunasivam, Raj; Lo, Mary; Stern, Mariana et al. (2018) The Role of Provider Characteristics in the Selection of Surgery or Radiation for Localized Prostate Cancer and Association With Quality of Care Indicators. Am J Clin Oncol :
Hamilton, Ann S; Fleming, Steven T; Wang, Dian et al. (2016) Clinical and Demographic Factors Associated With Receipt of Non Guideline-concordant Initial Therapy for Nonmetastatic Prostate Cancer. Am J Clin Oncol 39:55-63
Anderson, Roger T; Morris, Cyllene R; Kimmick, Gretchen et al. (2015) Patterns of locoregional treatment for nonmetastatic breast cancer by patient and health system factors. Cancer 121:790-9
Fleming, Steven T; Hamilton, Ann S; Sabatino, Susan A et al. (2014) Treatment patterns for prostate cancer: comparison of Medicare claims data to medical record review. Med Care 52:e58-64
Kimmick, Gretchen; Fleming, Steven T; Sabatino, Susan A et al. (2014) Comorbidity burden and guideline-concordant care for breast cancer. J Am Geriatr Soc 62:482-8
Wang, Dian; Ho, Alex; Hamilton, Ann S et al. (2014) Type and dose of radiotherapy used for initial treatment of non-metastatic prostate cancer. Radiat Oncol 9:47
Fleming, Steven T; Kimmick, Gretchen G; Sabatino, Susan A et al. (2012) Defining care provided for breast cancer based on medical record review or Medicare claims: information from the Centers for Disease Control and Prevention Patterns of Care Study. Ann Epidemiol 22:807-13
Hamilton, Ann S; Wu, Xiao-Cheng; Lipscomb, Joseph et al. (2012) Regional, provider, and economic factors associated with the choice of active surveillance in the treatment of men with localized prostate cancer. J Natl Cancer Inst Monogr 2012:213-20
Fleming, Steven T; Sabatino, Susan A; Kimmick, Gretchen et al. (2011) Developing a claim-based version of the ACE-27 comorbidity index: a comparison with medical record review. Med Care 49:752-60