Abstract

This grant is for the Fundus Photograph Reading Center for the Macular Photocoagulation Study (MPS). The MPS is a multi-center randomized clinical trial designed to answer the question: Is the use of argon laser photocoagulation to obliterate extrafoveal new vessel membranes of benefit in preventing loss of central vision in patients with Senile Macular Degeneration or Ocular Histoplasmosis. The Reading Center reviews all fundus photographs and fluorescein angiograms of patients entered into the study at the clinical centers for the following purposes: 1. To insure that patients selected for the MPS at the various clinical centers meet the eligibility criteria. 2. To insure that photocoagulation treatment is carried out according to protocol. 3. To determine complications associated with treatment. 4. To classify eyes according to distance of neovascularization from the center of the fovea. 5. To describe pathology present in eyes reaching defined points for both treated and not treated eyes.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01EY002546-08
Application #
3551216
Study Section
Vision Research and Training Committee (VSN)
Project Start
1979-01-01
Project End
1986-09-30
Budget Start
1986-01-01
Budget End
1986-09-30
Support Year
8
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

(1996) Five-year follow-up of fellow eyes of individuals with ocular histoplasmosis and unilateral extrafoveal or juxtafoveal choroidal neovascularization. Macular Photocoagulation Study Group. Arch Ophthalmol 114:677-88
(1995) The influence of treatment extent on the visual acuity of eyes treated with Krypton laser for juxtafoveal choroidal neovascularization. Macular Photocoagulation Study Group. Arch Ophthalmol 113:190-4
(1995) Laser photocoagulation for neovascular lesions nasal to the fovea. Results from clinical trials for lesions secondary to ocular histoplasmosis or idiopathic causes. Macular Photocoagulation Study Group. Arch Ophthalmol 113:56-61
(1994) Visual outcome after laser photocoagulation for subfoveal choroidal neovascularization secondary to age-related macular degeneration. The influence of initial lesion size and initial visual acuity. Macular Photocoagulation Study Group. Arch Ophthalmol 112:480-8
(1994) Laser photocoagulation for juxtafoveal choroidal neovascularization. Five-year results from randomized clinical trials. Macular Photocoagulation Study Group. Arch Ophthalmol 112:500-9
(1994) Persistent and recurrent neovascularization after laser photocoagulation for subfoveal choroidal neovascularization of age-related macular degeneration. Macular Photocoagulation Study Group. Arch Ophthalmol 112:489-99
(1994) Evaluation of argon green vs krypton red laser for photocoagulation of subfoveal choroidal neovascularization in the macular photocoagulation study. Macular Photocoagulation Study (MPS) Group. Arch Ophthalmol 112:1176-84
(1993) Five-year follow-up of fellow eyes of patients with age-related macular degeneration and unilateral extrafoveal choroidal neovascularization. Macular Photocoagulation Study Group. Arch Ophthalmol 111:1189-99
(1993) Laser photocoagulation of subfoveal neovascular lesions of age-related macular degeneration. Updated findings from two clinical trials. Macular Photocoagulation Study Group. Arch Ophthalmol 111:1200-9
(1987) Krypton laser photocoagulation for neovascular lesions of ocular histoplasmosis. Results of a randomized clinical trial. Macular Photocoagulation Study Group. Arch Ophthalmol 105:1499-507

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