Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project--Cooperative Agreements (U01)
Project #
3U01EY006859-06S2
Application #
3551975
Study Section
Vision Research and Training Committee (VSN)
Project Start
1990-06-01
Project End
1992-03-31
Budget Start
1990-09-30
Budget End
1992-03-31
Support Year
6
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Harvard University
Department
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Lin-Jones, Jennifer; Parker, Ed; Wu, Mike et al. (2004) Myosin 3A transgene expression produces abnormal actin filament bundles in transgenic Xenopus laevis rod photoreceptors. J Cell Sci 117:5825-34
Lin-Jones, Jennifer; Parker, Ed; Wu, Mike et al. (2003) Disruption of kinesin II function using a dominant negative-acting transgene in Xenopus laevis rods results in photoreceptor degeneration. Invest Ophthalmol Vis Sci 44:3614-21
Duncan, T; Swint, C; Smith, S B et al. (1999) Levels of retinoic acid and retinaldehyde dehydrogenase expression in eyes of the Mitf-vit mouse model of retinal degeneration. Mol Vis 5:9
Bora, N; Defoe, D; Smith, S B (1999) Evidence of decreased adhesion between the neural retina and retinal pigmented epithelium of the Mitfvit (vitiligo) mutant mouse. Cell Tissue Res 295:65-75
Smith, S B; Zhou, B K; Orlow, S J (1998) Expression of tyrosinase and the tyrosinase related proteins in the Mitfvit (vitiligo) mouse eye: implications for the function of the microphthalmia transcription factor. Exp Eye Res 66:403-10
Smith, S B; Brodjian, S; Desai, S et al. (1997) Glial fibrillary acidic protein (GFAP) is synthesized in the early stages of the photoreceptor cell degeneration of the mivit/mivit (vitiligo) mouse. Exp Eye Res 64:645-50
Evans, B L; Smith, S B (1997) Analysis of esterification of retinoids in the retinal pigmented epithelium of the Mitf-vit (vitiligo) mutant mouse. Mol Vis 3:11
Tang, M; Ruiz, M; Kosaras, B et al. (1996) Increased cell genesis in retinal pigment epithelium of perinatal vitiligo mutant mice. Invest Ophthalmol Vis Sci 37:1116-24
Sidman, R L; Kosaras, B; Tang, M (1996) Pigment epithelial and retinal phenotypes in the vitiligo mivit, mutant mouse. Invest Ophthalmol Vis Sci 37:1097-115
Smith, S B; Titelman, R; Hamasaki, D I (1996) Effects of basic fibroblast growth factor on the retinal degeneration of the mi(vit)/mi(vit) (vitiligo) mouse: a morphologic and electrophysiologic study. Exp Eye Res 63:565-77

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