This is an application to become one of the cooperating clinics in the Optic Neuritis Treatment Trial. The ONTT consists of 2 research components: (1) a clinical trial of the efficacy of oral prednisone and intravenous methylprednisolone in reducing residual optic nerve damage in patients with optic neuritis; and (2) a study of the natural history of optic neuritis. In this proposal we document our patient recruitment potential. The principal investigator saw 21 patients with optic neuritis meeting the listed study criteria within a 12 month period. In addition we provide data from 2 major medical centers in our referral area, willing to refer patients for the study, who have seen a total of 31 patients with optic neuritis, meeting the study criteria within a 12 months period. The ONTT is chaired by Roy W. Beck, M.D. at the University of South Florida College of Medicine (cooperative agreement award #U01-EY07212-01). The Data Coordinating Center is directed by Patrician Cleary at the Biostatistics Center of George Washington University (cooperative agreement award #U01-EY07460-01).

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project--Cooperative Agreements (U01)
Project #
7U01EY007695-03
Application #
3552096
Study Section
Vision Research and Training Committee (VSN)
Project Start
1989-07-01
Project End
1992-02-29
Budget Start
1989-07-01
Budget End
1990-02-28
Support Year
3
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Smith-Kettlewell Eye Research Institute
Department
Type
DUNS #
City
San Francisco
State
CA
Country
United States
Zip Code
94115