Funding Agency

Agency
National Institute of Health (NIH)
Institute
Food and Drug Administration (FDA)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01FD001431-02
Application #
3552213
Study Section
Bacteriology and Mycology Subcommittee 1 (BM)
Project Start
1987-06-01
Project End
1990-05-31
Budget Start
1988-06-01
Budget End
1989-05-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Medical Research Institute of San Fran
Department
Type
DUNS #
City
San Francisco
State
CA
Country
United States
Zip Code
94115

  Publications

Bermudez, L E; Martinelli, J; Petrofsky, M et al. (1994) Recombinant granulocyte-macrophage colony-stimulating factor enhances the effects of antibiotics against Mycobacterium avium complex infection in the beige mouse model. J Infect Dis 169:575-80
Bermudez, L E (1993) Production of transforming growth factor-beta by Mycobacterium avium-infected human macrophages is associated with unresponsiveness to IFN-gamma. J Immunol 150:1838-45
Bermudez, L E (1993) Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages. The role of nitric oxide. Clin Exp Immunol 91:277-81
Bermudez, L E; Wu, M; Petrofsky, M et al. (1992) Interleukin-6 antagonizes tumor necrosis factor-mediated mycobacteriostatic and mycobactericidal activities in macrophages. Infect Immun 60:4245-52
Bermudez, L E; Young, L S (1992) Tumor necrosis factor alpha stimulates mycobactericidal/mycobacteriostatic activity in human macrophages by a protein kinase C-independent pathway. Cell Immunol 144:258-68
Bermudez, L E; Petrofsky, M; Kolonoski, P et al. (1992) An animal model of Mycobacterium avium complex disseminated infection after colonization of the intestinal tract. J Infect Dis 165:75-9
Bermudez, L E; Young, L S (1991) Natural killer cell-dependent mycobacteriostatic and mycobactericidal activity in human macrophages. J Immunol 146:265-70
Bermudez, L E; Young, L S; Gupta, S (1990) 1,25 Dihydroxyvitamin D3-dependent inhibition of growth or killing of Mycobacterium avium complex in human macrophages is mediated by TNF and GM-CSF. Cell Immunol 127:432-41
Bermudez, L E; Young, L S (1990) Recombinant granulocyte-macrophage colony-stimulating factor activates human macrophages to inhibit growth or kill Mycobacterium avium complex. J Leukoc Biol 48:67-73
Bermudez, L E; Yau-Young, A O; Lin, J P et al. (1990) Treatment of disseminated Mycobacterium avium complex infection of beige mice with liposome-encapsulated aminoglycosides. J Infect Dis 161:1262-8

Showing the most recent 10 out of 14 publications