Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01GM094588-02
Application #
8306878
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
2
Fiscal Year
2011
Total Cost
$52,550
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Bailey, Lucas J; Sheehy, Kimberly M; Dominik, Pawel K et al. (2018) Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination. J Mol Biol 430:337-347
Mukherjee, Somnath; Griffin, Dionne H; Horn, James R et al. (2018) Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins. J Biol Chem 293:2815-2828
Sun, Jian; Paduch, Marcin; Kim, Sang-Ah et al. (2018) Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2. Proc Natl Acad Sci U S A 115:10010-10015
Schaefer, Zachary P; Bailey, Lucas J; Kossiakoff, Anthony A (2016) A polar ring endows improved specificity to an antibody fragment. Protein Sci 25:1290-8
Dominik, Pawel K; Borowska, Marta T; Dalmas, Olivier et al. (2016) Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs. Structure 24:300-9
Galilee, Meytal; Britan-Rosich, Elena; Griner, Sarah L et al. (2016) The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical. Structure 24:1936-1946
Mateja, Agnieszka; Paduch, Marcin; Chang, Hsin-Yang et al. (2015) Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Science 347:1152-5
Stuwe, Tobias; Correia, Ana R; Lin, Daniel H et al. (2015) Nuclear pores. Architecture of the nuclear pore complex coat. Science 347:1148-52
Dominik, Pawel K; Kossiakoff, Anthony A (2015) Phage display selections for affinity reagents to membrane proteins in nanodiscs. Methods Enzymol 557:219-45
Stuwe, Tobias; Bley, Christopher J; Thierbach, Karsten et al. (2015) Architecture of the fungal nuclear pore inner ring complex. Science 350:56-64

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