Abstract

We will apply transdisciplinary, data-driven and multi-scale modeling approaches to inform timely policy decisions. We will specifically evaluate the effectiveness and cost-effectiveness of vaccination strategies to control rabies, polio and pertussis. Our models will capture epidemiological, clinical, behavioral and socio- economic factors pertinent to the implementation, effectiveness and health economics of policy decisions. Our results will enhance our understanding of health decision-making and inform intervention strategies to improve vaccination rates nationally and internationally.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01GM105627-05
Application #
9266796
Study Section
Special Emphasis Panel (ZEB1-OSR-C (J2)S)
Program Officer
Marcus, Stephen
Project Start
2013-07-10
Project End
2018-03-31
Budget Start
2017-04-01
Budget End
2018-03-31
Support Year
5
Fiscal Year
2017
Total Cost
$274,232
Indirect Cost
$75,639

  Institution

Name
Yale University
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Medley, Graham F; Blok, David J; Crump, Ronald E et al. (2018) Policy Lessons From Quantitative Modeling of Leprosy. Clin Infect Dis 66:S281-S285
Rock, Kat S; Ndeffo-Mbah, Martial L; Castaño, Soledad et al. (2018) Assessing Strategies Against Gambiense Sleeping Sickness Through Mathematical Modeling. Clin Infect Dis 66:S286-S292
Sah, Pratha; Medlock, Jan; Fitzpatrick, Meagan C et al. (2018) Optimizing the impact of low-efficacy influenza vaccines. Proc Natl Acad Sci U S A 115:5151-5156
Durham, David P; Fitzpatrick, Meagan C; Ndeffo-Mbah, Martial L et al. (2018) Evaluating Vaccination Strategies for Zika Virus in the Americas. Ann Intern Med 168:621-630
Marshall, Brandon D L; Goedel, William C; King, Maximilian R F et al. (2018) Potential effectiveness of long-acting injectable pre-exposure prophylaxis for HIV prevention in men who have sex with men: a modelling study. Lancet HIV 5:e498-e505
Grantz, Kyra H; Chabaari, Winnie; Samuel, Ramolotja Kagiso et al. (2018) Spatial distribution of leprosy in India: an ecological study. Infect Dis Poverty 7:20
Fitzpatrick, Meagan C; Gray, Glenda E; Galvani, Alison P (2018) The Challenge of Vanquishing HIV for the Next Generation-Facing the Future. JAMA Pediatr 172:609-610
Ndeffo-Mbah, Martial L; Vigliotti, Vivian S; Skrip, Laura A et al. (2018) Dynamic Models of Infectious Disease Transmission in Prisons and the General Population. Epidemiol Rev 40:40-57
Lee, Bruce Y; Bartsch, Sarah M; Skrip, Laura et al. (2018) Are the London Declaration's 2020 goals sufficient to control Chagas disease?: Modeling scenarios for the Yucatan Peninsula. PLoS Negl Trop Dis 12:e0006337
Castro, Lauren A; Fox, Spencer J; Chen, Xi et al. (2017) Assessing real-time Zika risk in the United States. BMC Infect Dis 17:284

Showing the most recent 10 out of 41 publications