Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01HD028514-05
Application #
2201162
Study Section
Special Emphasis Panel (SRC (12))
Project Start
1991-09-01
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Mitra, J; Schultz, R M (1996) Regulation of the acquisition of meiotic competence in the mouse: changes in the subcellular localization of cdc2, cyclin B1, cdc25C and wee1, and in the concentration of these proteins and their transcripts. J Cell Sci 109 ( Pt 9):2407-15
Ho, Y; Wigglesworth, K; Eppig, J J et al. (1995) Preimplantation development of mouse embryos in KSOM: augmentation by amino acids and analysis of gene expression. Mol Reprod Dev 41:232-8
Ning, X; Ward, C R; Kopf, G S (1995) Activation of a Gi protein in digitonin/cholate-solubilized membrane preparations of mouse sperm by the zona pellucida, an egg-specific extracellular matrix. Mol Reprod Dev 40:355-63
Ho, Y; Doherty, A S; Schultz, R M (1994) Mouse preimplantation embryo development in vitro: effect of sodium concentration in culture media on RNA synthesis and accumulation and gene expression. Mol Reprod Dev 38:131-41
Moos, J; Kalab, P; Kopf, G S et al. (1994) Rapid, nonradioactive, and quantitative method to analyze zona pellucida modifications in single mouse eggs. Mol Reprod Dev 38:91-3
Doherty, A S; Temeles, G L; Schultz, R M (1994) Temporal pattern of IGF-I expression during mouse preimplantation embryogenesis. Mol Reprod Dev 37:21-6
Eppig, J J; Schultz, R M; O'Brien, M et al. (1994) Relationship between the developmental programs controlling nuclear and cytoplasmic maturation of mouse oocytes. Dev Biol 164:1-9
Kalab, P; Visconti, P; Leclerc, P et al. (1994) p95, the major phosphotyrosine-containing protein in mouse spermatozoa, is a hexokinase with unique properties. J Biol Chem 269:3810-7
Anbari, K; Schultz, R M (1993) Effect of sodium and betaine in culture media on development and relative rates of protein synthesis in preimplantation mouse embryos in vitro. Mol Reprod Dev 35:24-8
Kalab, P; Schultz, R M; Kopf, G S (1993) Modifications of the mouse zona pellucida during oocyte maturation: inhibitory effects of follicular fluid, fetuin, and alpha 2HS-glycoprotein. Biol Reprod 49:561-7

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