Neural Tube Defects in Mice

Sadler, Thomas W.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
• Type: Research Project--Cooperative Agreements (U01)
• Project #: 5U01HD028860-05
• Application #: 2201381
• Study Section: Special Emphasis Panel (SRC (09))
• Project Start: 1992-05-01
• Project End: 1998-04-30
• Budget Start: 1996-05-01
• Budget End: 1998-04-30
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: University of North Carolina Chapel Hill
• Department: Anatomy/Cell Biology
• Type: Schools of Medicine
• DUNS #: 078861598
• City: Chapel Hill
• State: NC
• Country: United States
• Zip Code: 27599

Publications

Sulik, K K; Dehart, D B; Rogers, J M et al. (1995) Teratogenicity of low doses of all-trans retinoic acid in presomite mouse embryos. Teratology 51:398-403

Homanics, G E; Maeda, N; Traber, M G et al. (1995) Exencephaly and hydrocephaly in mice with targeted modification of the apolipoprotein B (Apob) gene. Teratology 51:1-10

Sadler, T W; Liu, E T; Augustine, K A (1995) Antisense targeting of engrailed-1 causes abnormal axis formation in mouse embryos. Teratology 51:292-9

Augustine, K A; Liu, E T; Sadler, T W (1995) Antisense inhibition of engrailed genes in mouse embryos reveals roles for these genes in craniofacial and neural tube development. Teratology 51:300-10

Augustine, K; Liu, E T; Sadler, T W (1993) Antisense attenuation of Wnt-1 and Wnt-3a expression in whole embryo culture reveals roles for these genes in craniofacial, spinal cord, and cardiac morphogenesis. Dev Genet 14:500-20

Wei, X; Sulik, K K (1993) Pathogenesis of craniofacial and body wall malformations induced by ochratoxin A in mice. Am J Med Genet 47:862-71

Sulik, K K; Sadler, T W (1993) Postulated mechanisms underlying the development of neural tube defects. Insights from in vitro and in vivo studies. Ann N Y Acad Sci 678:8-21