The Adolescent AIDS Program (AAP) at Montefiore Medical Center, Einstein College of Medicine, in the Bronx, NY is re-competing to be an Adolescent Medicine Trials Unit to implement clinical and behavioral Studies in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The AAP believes that its 23 years of experience and leadership in providing the highest quality clinical care and research, combined with innovative strategies for community outreach will offer important scientific and operational contributions to the ATN.
The Specific Aims of the AAP's participation in the ATN are to: 1) contribute to the advancement of the scientific agenda of the ATN through participating in protocol teams, writing/reviewing protocols and research papers and disseminating of key findings;2) advance HIV prevention and care by recruiting and retaining HIV+ and at-risk youth ages 13-24 years into all relevant ATN trials;3) provide a comprehensive array of clinical and mental health services to youth to facilitate their clinical care and enrollment into trials while ensuring their rights and safety as research volunteers;4) contribute to the prevention of HIV via Connect to Protect innovative outreach prevention strategies and community mobilization and structural change such as the Bronx Knows and 5) contribute to the effective operations of the ATN via participation in calls, meetings and committees. The goals of the RFA include the development and implementation of behavioral, community-based and translational, prophylactic, therapeutic and vaccine trials with HIV+ and at-risk youth. The success of these intervention studies will facilitate better clinical and behavioral management for HIV infected youth as well as make a significant contribution to the prevention of HIV infection among youth. The AAP is uniquely positioned to meet these goals both through experience as well as its population of HIV positive and at-risk youth living in the Bronx, NY. In 2009, the AAP cared for 134 HIV+ patients, 62% male and 98% ethnic/racial minorities. The heavy burden of HIV faced by Bronx residents and youth necessitates continued research. As the borough with the poorest congressional district in the nation, the health status of the 1.3 million Bronx residents continues to lag behind other residents of NYC. Participation in the ATN will help the AAP to continue to address the public health issues of HIV/AIDS in the Bronx, NY.

Public Health Relevance

Adolescents from communities of color as well as young men who have sex with men continue to experience disproportionate rates of HIV infection. A clinical trials network which addresses research to the care and prevention needs of these youth is crucial for addressing the HIV epidemic. The Adolescent AIDS Program represents a high quality clinical and research site in the heavily impacted community of the Bronx, NY.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01HD040499-14
Application #
8658307
Study Section
Special Emphasis Panel (ZHD1)
Program Officer
Russo, Denise
Project Start
2001-04-16
Project End
2016-02-29
Budget Start
2014-03-01
Budget End
2015-02-28
Support Year
14
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
City
Bronx
State
NY
Country
United States
Zip Code
10461
Boyer, Cherrie B; Greenberg, Lauren; Chutuape, Kate et al. (2017) Exchange of Sex for Drugs or Money in Adolescents and Young Adults: An Examination of Sociodemographic Factors, HIV-Related Risk, and Community Context. J Community Health 42:90-100
Nichols, Sharon L; Bethel, James; Kapogiannis, Bill G et al. (2016) Antiretroviral treatment initiation does not differentially alter neurocognitive functioning over time in youth with behaviorally acquired HIV. J Neurovirol 22:218-30
Futterman, Donna; Stafford, Stephen; Meissner, Paul et al. (2016) Ten Sites, 10 Years, 10 Lessons: Scale-up of Routine HIV Testing at Community Health Centers in the Bronx, New York. Public Health Rep 131 Suppl 1:53-62
Hanna, David B; Felsen, Uriel R; Ginsberg, Mindy S et al. (2016) Increased Antiretroviral Therapy Use and Virologic Suppression in the Bronx in the Context of Multiple HIV Prevention Strategies. AIDS Res Hum Retroviruses 32:955-963
Chutuape, Kate S; Willard, Nancy; Walker, Bendu C et al. (2015) A Tailored Approach to Launch Community Coalitions Focused on Achieving Structural Changes: Lessons Learned From a HIV Prevention Mobilization Study. J Public Health Manag Pract 21:546-55
Boyer, Cherrie B; Hightow-Weidman, Lisa; Bethel, James et al. (2013) An assessment of the feasibility and acceptability of a friendship-based social network recruitment strategy to screen at-risk African American and Hispanic/Latina young women for HIV infection. JAMA Pediatr 167:289-96
Lee, Sonia; Kapogiannis, Bill G; Flynn, Patricia M et al. (2013) Comprehension of a simplified assent form in a vaccine trial for adolescents. J Med Ethics 39:410-2
Doll, Mimi; Harper, Gary W; Robles-Schrader, Grisel M et al. (2012) Perspectives of community partners and researchers about factors impacting coalition functioning over time. J Prev Interv Community 40:87-102
Robles-Schrader, Grisel M; Harper, Gary W; Purnell, Marjorie et al. (2012) Differential challenges in coalition building among HIV prevention coalitions targeting specific youth populations. J Prev Interv Community 40:131-48
Willard, Nancy; Chutuape, Kate; Stines, Stephanie et al. (2012) Bridging the gap between individual-level risk for HIV and structural determinants: using root cause analysis in strategic planning. J Prev Interv Community 40:103-17

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