The goal of this proposal is to collaborate with the Adolescent Trials Network (ATN) to reduce the spread of HIV disease and mitigate its effects in young people ages 13-24, and to enhance ATN studies by accessing a large number of youth from a smaller, primarily African American, mid-western city highly affected by the recent economic crisis. We propose to do this by conducting interdisciplinary clinical trials in a newly established Adolescent Medicine Trials Unit (ATU) in the only pediatric and adolescent HIV clinics In Detroit, Ml, the U.S. city with the highest percentage of African Americans according to the 2000 Census.

Public Health Relevance

An ATU in Detroit would provide the ATN with access to further information about Midwestern adolescents and young adults with HIV. Chicago is the only midwestern city represented in the ATN. Detroit has the second largest African American population of any US city and is unique in its demographics and disproportionate """"""""hit"""""""" from the current depression. Our youth experience distinct challenges and do not have access to ATN treatment studies. Inclusion will result in a more expansive ATN network in the Midwest.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01HD068030-03
Application #
8442202
Study Section
Special Emphasis Panel (ZHD1-DSR-A (15))
Program Officer
Russo, Denise
Project Start
2011-04-07
Project End
2016-02-29
Budget Start
2013-03-01
Budget End
2014-02-28
Support Year
3
Fiscal Year
2013
Total Cost
$351,001
Indirect Cost
$120,079
Name
Wayne State University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
001962224
City
Detroit
State
MI
Country
United States
Zip Code
48202
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Kahn, Jessica A; Rudy, Bret J; Xu, Jiahong et al. (2016) Prevalence and risk factors for oral DNA tumor viruses in HIV-infected youth. J Med Virol 88:1944-52
Chutuape, Kate S; Willard, Nancy; Walker, Bendu C et al. (2015) A Tailored Approach to Launch Community Coalitions Focused on Achieving Structural Changes: Lessons Learned From a HIV Prevention Mobilization Study. J Public Health Manag Pract 21:546-55
Kahn, Jessica A; Rudy, Bret J; Xu, Jiahong et al. (2015) Behavioral, immunologic, and virologic correlates of oral human papillomavirus infection in HIV-infected youth. Sex Transm Dis 42:246-52