CF is a multi-system disease, however, infection in the airways is the most important clinical problem. Initial infections are caused by a variety of organisms, and often can be eradicated by antibiotics (1, 2). Later in the disease, P. aeruginosa establishes permanent colonization (1). This colonization results in persistent respiratory symptoms, airway inflammation and eventual respiratory failure.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01HL102288-03
Application #
8379824
Study Section
Special Emphasis Panel (ZHL1-CSR-H)
Project Start
Project End
2014-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
3
Fiscal Year
2012
Total Cost
$2,044,958
Indirect Cost
$527,246
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
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