Abstract

The Children's Cancer Study Group is composed of a group of cooperative pediatric centers, and provides an administrative and communicative structure for the performance of cooperatively designed clinical studies for the treatment of children with leukemia and solid tumors. These investigations involve a multidisciplinary approach including multiple agent chemotherapy, surgery, radiation, immunotherapy, and other modalities. The objective of these studies is to establish with maximum efficiency therapeutic regimens for these diseases that will provide an optimal outcome, with minimal untoward effects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA007431-25
Application #
3555894
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Project Start
1978-12-01
Project End
1988-11-30
Budget Start
1988-02-29
Budget End
1988-11-30
Support Year
25
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Children's Memorial Hospital (Chicago)
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60614

  Publications

Wacker, Pierre; Land, Vita J; Camitta, Bruce M et al. (2007) Allergic reactions to E. coli L-asparaginase do not affect outcome in childhood B-precursor acute lymphoblastic leukemia: a Children's Oncology Group Study. J Pediatr Hematol Oncol 29:627-32
Ravindranath, Y; Chang, M; Steuber, C P et al. (2005) Pediatric Oncology Group (POG) studies of acute myeloid leukemia (AML): a review of four consecutive childhood AML trials conducted between 1981 and 2000. Leukemia 19:2101-16
Shamberger, Robert C; LaQuaglia, Michael P; Gebhardt, Mark C et al. (2003) Ewing sarcoma/primitive neuroectodermal tumor of the chest wall: impact of initial versus delayed resection on tumor margins, survival, and use of radiation therapy. Ann Surg 238:563-7; discussion 567-8
Pollock, Brad H; Jenson, Hal B; Leach, Charles T et al. (2003) Risk factors for pediatric human immunodeficiency virus-related malignancy. JAMA 289:2393-9
Davies, Stella M; Bhatia, Smita; Ross, Julie A et al. (2002) Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia. Blood 100:67-71
Mitchell, Claudia; Fausto, Nelson (2002) Bone marrow-derived hepatocytes : rare but promising. Am J Pathol 161:349-50
Lacayo, N J; Lum, B L; Becton, D L et al. (2002) Pharmacokinetic interactions of cyclosporine with etoposide and mitoxantrone in children with acute myeloid leukemia. Leukemia 16:920-7
Ferguson, W S; Harris, M B; Goorin, A M et al. (2001) Presurgical window of carboplatin and surgery and multidrug chemotherapy for the treatment of newly diagnosed metastatic or unresectable osteosarcoma: Pediatric Oncology Group Trial. J Pediatr Hematol Oncol 23:340-8
Saylors 3rd, R L; Stine, K C; Sullivan, J et al. (2001) Cyclophosphamide plus topotecan in children with recurrent or refractory solid tumors: a Pediatric Oncology Group phase II study. J Clin Oncol 19:3463-9
Hurwitz, C A; Strauss, L C; Kepner, J et al. (2001) Paclitaxel for the treatment of progressive or recurrent childhood brain tumors: a pediatric oncology phase II study. J Pediatr Hematol Oncol 23:277-81

Showing the most recent 10 out of 24 publications