Our overall objective is to remain a full and active member of the Gynecologic Oncology Group and continue our participation in cooperative clinical trials conducted by the Group. In these trials, the Gynecologic Oncology group uses accepted and new experimental treatment methods in a large number of patients with all types of gynecologic cancer. Significant improvement of treatment results have been achieved in patients with gynecologic cancer by means of this multidisciplinary approach. The past performance and the track record set by the GOG provides for optimism in the improvement of the 5-year survival and quality of life of gynecologic cancer patients. Our institution will continue to register with the Group's Statistical Office all new gyn cancer patients entering our hospital. We will continue to enroll all eligible patients in active GOG protocols. We will participate in the following open protocols: Protocols #49, 56, 59, 64 dealing with the management of cervical carcinoma Protocols #34, 48 studying endometrial cancer Protocol #40 dealing with uterine sarcoma Protocols #36, 37 for the study of vulvar cancer and Protocol #55 for the study of trophoblastic disease. Protocols #4l, 44, 45, 52, 60, 6l dealing with treatment of ovarian cancers. All protocols testing phase II drugs in multiple sites of gyn cancer. Our participation will extend also to all protocols activated by the Group in the future.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA016386-10
Application #
3556375
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Project Start
1978-06-01
Project End
1988-04-30
Budget Start
1985-05-01
Budget End
1986-04-30
Support Year
10
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
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Tate Thigpen, J; Blessing, John A; DeGeest, Koen et al. (2004) Cisplatin as initial chemotherapy in ovarian carcinosarcomas: a Gynecologic Oncology Group study. Gynecol Oncol 93:336-9
Ganz, Patricia A; Moinpour, Carol M; Pauler, Donna K et al. (2003) Health status and quality of life in patients with early-stage Hodgkin's disease treated on Southwest Oncology Group Study 9133. J Clin Oncol 21:3512-9
Thigpen, J Tate; Blessing, John A; Olt, George et al. (2003) Cisplatin as second-line therapy in ovarian carcinoma treated initially with single-agent paclitaxel: a Gynecologic Oncology Group study. Gynecol Oncol 90:581-6
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Calkins, A R; Harrison, C R; Fowler Jr, W C et al. (1999) Hyperfractionated radiation therapy plus chemotherapy in locally advanced cervical cancer: results of two phase I dose-escalation Gynecologic Oncology Group trials. Gynecol Oncol 75:349-55
Walton, L A; Blessing, J A; Homesley, H D (1989) Adverse effects of intraperitoneal fluorouracil in patients with optimal residual ovarian cancer after second-look laparotomy: a Gynecologic Oncology Group Study. J Clin Oncol 7:466-70
Asbury, R F; Blessing, J A; Mortel, R et al. (1987) Aminothiadiazole (NSC #4728) in patients with advanced cervical carcinoma. A phase II study of the Gynecologic Oncology Group. Am J Clin Oncol 10:299-301

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