The objective of Indiana University Medical Center (IUMC) is to continue to be one of the leading contributors to the Gynecologic Oncology Group. Through a multidisciplinary effort, IUMC will participate in this collaborative research project to improve the results of treatment for women with pelvic cancer and assist in developing more effective means for prevention, detection, diagnosis, therapy and follow-up. The long range goals are to improve patient care, prolong survival, rapidly assess new treatment methods and the dissemination of knowledge. IUMC will enhance the objectives of the Group as a whole by: 1.) Participation in all protocols available through the Gynecologic Oncology Group. 2.) Continuation of 100% completeness of quality data submission. 3.) Evaluability rates well above the membership criteria standards. 4.) A continued high patient accrual. 5.) Significant scientific contributions and involvement in future protocol development. 6.) Continued publications. 7.) Continued national level support of the GOG on numerous committees. 8.) Continuation of support extended to other member institutions for data management training. 9.) Continued aggressive effort by all IUMC GOG personnel. 10.) Continued success in all areas of this research endeavor.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA021720-09
Application #
3556629
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Project Start
1978-07-01
Project End
1988-04-30
Budget Start
1986-05-01
Budget End
1987-04-30
Support Year
9
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Type
Schools of Medicine
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Sutton, Gregory; Axelrod, Janice H; Bundy, Brian N et al. (2006) Adjuvant whole abdominal irradiation in clinical stages I and II papillary serous or clear cell carcinoma of the endometrium: a phase II study of the Gynecologic Oncology Group. Gynecol Oncol 100:349-54
Tate Thigpen, J; Blessing, John A; DeGeest, Koen et al. (2004) Cisplatin as initial chemotherapy in ovarian carcinosarcomas: a Gynecologic Oncology Group study. Gynecol Oncol 93:336-9
Thigpen, J Tate; Blessing, John A; Olt, George et al. (2003) Cisplatin as second-line therapy in ovarian carcinoma treated initially with single-agent paclitaxel: a Gynecologic Oncology Group study. Gynecol Oncol 90:581-6
Keys, Henry M; Bundy, Brian N; Stehman, Frederick B et al. (2003) Radiation therapy with and without extrafascial hysterectomy for bulky stage IB cervical carcinoma: a randomized trial of the Gynecologic Oncology Group. Gynecol Oncol 89:343-53
Spirtos, Nick M; Westby, Cynthia M; Averette, Hervy E et al. (2002) Blood transfusion and the risk of recurrence in squamous cell carcinoma of the cervix: a gynecologic oncology group study. Am J Clin Oncol 25:398-403
Zaino, R; Whitney, C; Brady, M F et al. (2001) Simultaneously detected endometrial and ovarian carcinomas--a prospective clinicopathologic study of 74 cases: a gynecologic oncology group study. Gynecol Oncol 83:355-62
Moore, D H; Valea, F; Walton, L A et al. (1995) A phase I study of intraperitoneal interferon-alpha 2b and intravenous cis-platinum plus cyclophosphamide chemotherapy in patients with untreated stage III epithelial ovarian cancer: a Gynecologic Oncology Group pilot study. Gynecol Oncol 59:267-72
Broun, E R; Belinson, J L; Berek, J S et al. (1994) Salvage therapy for recurrent and refractory ovarian cancer with high-dose chemotherapy and autologous bone marrow support: a Gynecologic Oncology Group pilot study. Gynecol Oncol 54:142-6
Malfetano, J H; Blessing, J A; Jacobs, A J (1993) A phase II trial of Didemnin B (NSC #335319) in patients with previously treated epithelial ovarian cancer. A Gynecologic Oncology Group Study. Am J Clin Oncol 16:47-9
Slayton, R E; Blessing, J A; Sutton, G P et al. (1986) Phase II clinical trial of diaziquone in the treatment of patients with epithelial ovarian cancer: a Gynecologic Oncology Group Study. Cancer Treat Rep 70:309-10

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