Abstract

This project aims to improve the survival and quality of life of women with gynecologic cancer. Group wide protocols carefully conceived and directed at specific disease entities will be used. These protocols were developed within the Gynecologic Oncology Group (G.O.G) with input from gynecologists, medical oncologists, radiation therapists, pathologists, immunotherapists and oncology nurses. Eligible patients are treated via methods outlined in the protocol. The continuing care of the patients is rigidly supervised by Prtotocol Chairman and by regular G.O.G. reporting systems. Uniform treatment of large numbers of patients enables the G.O.G. to assess treatment methods and results within a reasonable period of time. Successful results can be widely disseminated with improvement of care, prolongation of life, and quality of life at a national level.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA023073-08
Application #
3556678
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Project Start
1978-06-01
Project End
1988-04-30
Budget Start
1985-05-01
Budget End
1986-04-30
Support Year
8
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Sutton, Gregory; Axelrod, Janice H; Bundy, Brian N et al. (2006) Adjuvant whole abdominal irradiation in clinical stages I and II papillary serous or clear cell carcinoma of the endometrium: a phase II study of the Gynecologic Oncology Group. Gynecol Oncol 100:349-54
Schilder, Russell J; Blessing, John; Cohn, David E (2005) Evaluation of gemcitabine in previously treated patients with non-squamous cell carcinoma of the cervix: a phase II study of the Gynecologic Oncology Group. Gynecol Oncol 96:103-7
Tate Thigpen, J; Blessing, John A; DeGeest, Koen et al. (2004) Cisplatin as initial chemotherapy in ovarian carcinosarcomas: a Gynecologic Oncology Group study. Gynecol Oncol 93:336-9
Thigpen, J Tate; Blessing, John A; Olt, George et al. (2003) Cisplatin as second-line therapy in ovarian carcinoma treated initially with single-agent paclitaxel: a Gynecologic Oncology Group study. Gynecol Oncol 90:581-6
Keys, Henry M; Bundy, Brian N; Stehman, Frederick B et al. (2003) Radiation therapy with and without extrafascial hysterectomy for bulky stage IB cervical carcinoma: a randomized trial of the Gynecologic Oncology Group. Gynecol Oncol 89:343-53
Spirtos, Nick M; Westby, Cynthia M; Averette, Hervy E et al. (2002) Blood transfusion and the risk of recurrence in squamous cell carcinoma of the cervix: a gynecologic oncology group study. Am J Clin Oncol 25:398-403
Manetta, A; Blessing, J A; Mann, W J et al. (1995) A phase II study of fazarabine (NSC 281272) in patients with advanced squamous cell carcinoma of the cervix. A Gynecologic Oncology Group study. Am J Clin Oncol 18:439-40
Moore, D H; Valea, F; Walton, L A et al. (1995) A phase I study of intraperitoneal interferon-alpha 2b and intravenous cis-platinum plus cyclophosphamide chemotherapy in patients with untreated stage III epithelial ovarian cancer: a Gynecologic Oncology Group pilot study. Gynecol Oncol 59:267-72
Sutton, G P; Blessing, J A; Barrett, R J et al. (1994) Phase II trial of menogaril in patients with squamous carcinoma of the cervix: a Gynecologic Oncology Group study. Gynecol Oncol 52:229-31
Russell, M; Thompson, F; Spier, C et al. (1993) Expression of the EVI1 gene in chronic myelogenous leukemia in blast crisis. Leukemia 7:1654-7

Showing the most recent 10 out of 15 publications