Abstract

During the past six years, the Bowman Gray School of Medicine Oncology Research Center has developed a collaborative relationship with our regional oncologists known as the Piedmont Oncology Association. This group of 86 cancer specialists has participated in clinical research trials and to date has entered 1,300+ patients on study. Although the quality of participation by the extramural members is generally equal to the quality in the Center, many difficulties and impediments derived from the absence of funding to develop the required operations office and data collection and management. Nevertheless, this regional collaborative group has made significant contributions to completed studies as indicated in the attached bibliography. This application seeks to obtain adequate funding to further develop and maintain a regional collaborative cancer clinical trials group.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
3U10CA033499-04S1
Application #
3557291
Study Section
(SRC)
Project Start
1982-07-01
Project End
1987-06-30
Budget Start
1985-07-01
Budget End
1987-06-30
Support Year
4
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
Wake Forest University Health Sciences
Department
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106

  Publications

Kimmick, Gretchen G; Shelton, Brent J; Case, L Douglas et al. (2002) Long-term follow-up of a phase II trial studying a weekly doxorubicin-based multiple drug adjuvant therapy for stage II node-positive carcinoma of the breast. Breast Cancer Res Treat 72:233-43
Jackson Jr, D V; Craig, J B; Spurr, C L et al. (1990) Vincristine infusion with CHOP-CCNU in diffuse large-cell lymphoma. Cancer Invest 8:7-12
Powell, B L; Capizzi, R L; Muss, H B et al. (1989) Low-dose ara-C therapy for acute myelogenous leukemia in elderly patients. Leukemia 3:23-8
Muss, H B; Wells, H B; Paschold, E H et al. (1988) Megestrol acetate versus tamoxifen in advanced breast cancer: 5-year analysis--a phase III trial of the Piedmont Oncology Association. J Clin Oncol 6:1098-106
Jackson Jr, D V; Case, L D; Zekan, P J et al. (1988) Improvement of long-term survival in extensive small-cell lung cancer. J Clin Oncol 6:1161-9
Powell, B L; Capizzi, R L; Jackson, D V et al. (1988) Low dose Ara-C for patients with myelodysplastic syndromes. Leukemia 2:153-6
Powell, B L; Craig, J B; Muss, H B et al. (1988) Phase II trial of high-dose cytosine arabinoside and cisplatin in recurrent squamous carcinoma of the head and neck. A Piedmont Oncology Association Study. Am J Clin Oncol 11:550-2
Muss, H B; McNamara, M J; Connelly, R A (1988) Follow-up after stage II breast cancer: a comparative study of relapsed versus nonrelapsed patients. Am J Clin Oncol 11:451-5
Jackson Jr, D V; Spurr, C L; Caponera, M E et al. (1987) Vinblastine infusion in non-Hodgkin's lymphomas: lack of total cross-resistance with vincristine. Cancer Invest 5:535-9
Craig, J B; Powell, B L; Jackson, D V et al. (1987) Phase II trial of high-dose cytarabine and cisplatin in locoregional previously untreated squamous carcinoma of the head and neck: a Piedmont Oncology Association Study. Cancer Treat Rep 71:151-3

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