The NSABP Cooperative Group Outreach Program proposed in this application will increase the number of patients receiving state of the art cancer care by introducing clinical trial participation further into the community setting. Since 1978, the NSABP has maintained a Cancer Control Network Program as part of the CGOP. Community physicians were provided support and information necessary to successfully conduct and document the treatment regimens accurately and effectively. A detailed review and analysis of the Cancer Control Network Program is presented. This current proposal will maintain and expand the ongoing Network Program through twenty-four geographically dispersed local networks each designed to achieve the program objectives which include, in addition to entry of patients into clinical trials, a) improving the skills of community physicians and other health professionals through continuing education, b) developing and maintaining high standards of care by providing necessary support services and instituting quality control procedures and c) disseminating new treatment information rapidly. Additional program-wide efforts will include the promotion of clinical trial participation in regions where patient entry to date has been limited, the development and evaluation of innovative methods of technology transfer, and participation in DCPC-sponsored evaluation of community programs. The introduction of new NSABP Network institutions provides a unique resource to better measure in a prospective fashion, the impact of CGOP on community cancer care. A systematic evaluation of several possible interventions is proposed.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA039086-03
Application #
3558256
Study Section
(SRC)
Project Start
1985-02-01
Project End
1987-11-30
Budget Start
1986-12-01
Budget End
1987-11-30
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Fisher, E R; Anderson, S; Tan-Chiu, E et al. (2001) Fifteen-year prognostic discriminants for invasive breast carcinoma: National Surgical Adjuvant Breast and Bowel Project Protocol-06. Cancer 91:1679-87
Mamounas, E; Wieand, S; Wolmark, N et al. (1999) Comparative efficacy of adjuvant chemotherapy in patients with Dukes' B versus Dukes' C colon cancer: results from four National Surgical Adjuvant Breast and Bowel Project adjuvant studies (C-01, C-02, C-03, and C-04) J Clin Oncol 17:1349-55
Wolmark, N; Rockette, H; Mamounas, E et al. (1999) Clinical trial to assess the relative efficacy of fluorouracil and leucovorin, fluorouracil and levamisole, and fluorouracil, leucovorin, and levamisole in patients with Dukes' B and C carcinoma of the colon: results from National Surgical Adjuvant Breast J Clin Oncol 17:3553-9
Fisher, E R; Dignam, J; Tan-Chiu, E et al. (1999) Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) eight-year update of Protocol B-17: intraductal carcinoma. Cancer 86:429-38
Fisher, B; Dignam, J; Wolmark, N et al. (1998) Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17. J Clin Oncol 16:441-52
Dignam, J J; Bryant, J; Wieand, H S et al. (1998) Early stopping of a clinical trial when there is evidence of no treatment benefit: protocol B-14 of the National Surgical Adjuvant Breast and Bowel Project. Control Clin Trials 19:575-88
Fisher, B; Bryant, J; Wolmark, N et al. (1998) Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J Clin Oncol 16:2672-85
Fisher, B; Dignam, J; Wolmark, N et al. (1997) Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer. J Natl Cancer Inst 89:1673-82
Fisher, B; Anderson, S; Wickerham, D L et al. (1997) Increased intensification and total dose of cyclophosphamide in a doxorubicin-cyclophosphamide regimen for the treatment of primary breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-22. J Clin Oncol 15:1858-69
Fisher, B; Brown, A; Mamounas, E et al. (1997) Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18. J Clin Oncol 15:2483-93

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