) The University of Illinois Hospital and affiliated Veteran's Administration West Side Medical Center both serve predominantly minority populations. There has been a long history and strong commitment from both institutions to serve this population in the city of Chicago. The objectives of the proposed University of Illinois Minority-Based CCOP (MBCCOP) which are the basis for this application are: 1. To increase minority participation in clinical cancer research protocols by identifying recruitment an retention goals with the collaboration of physicians, hospitals, clinical staff, and community leaders; 2. To increase the understanding, awareness, and involvement of health care providers, community leader and local organizations in the program; 2. To improve access to state-of-the-art treatment and cancer prevention and control research for minority individuals; 3. To increase the involvement of health care providers in cancer prevention and control studies; 4. To provide a base for extending cancer control advances to the minority population; 5. To study issues of minority recruitment to clinical trials. These objectives will be met by establishing a minority clinical research headquarters which utilizes the research bases of Cancer and Leukemia Group B (CALGB), Children's Cancer Group (CCG), Radiation Therapy Oncology Group (RTOG), and Gynecologic Oncology Group (GOG). The MBCCOP headquarters will be located at University of Illinois and will coordinate participation of p a t i e nts from the University of Illinois and West Side Veteran's Administration. An extensive network of affiliations have been put into place with primary care sites and community organizations. This will provide the patient base to allow better recruitment of minority patients to cancer control and prevention trials. Furthermore, University of Illinois faculty from the School of Public Health (Warnecke), College of Nursing (Ferrans), and the College of Social Work (Giachello) with expertise and experience in cancer control and prevention trials and quality of life studies in minority patients will act as co-investigators assisting in the implementation of these trials and assisting in evaluating their effectiveness in terms of recruitment and retention of minorities. The University of Illinois MBCCOP will provide an identifiable center committed to excellence in cancer care for the underserved communities of Chicago.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
1U10CA074811-01
Application #
2357041
Study Section
Special Emphasis Panel (ZCA1-RLB-7 (J3))
Project Start
1997-08-15
Project End
2000-07-31
Budget Start
1997-08-15
Budget End
1998-07-31
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Samlowski, Wolfram E; Moon, James; Witter, Merle et al. (2017) High frequency of brain metastases after adjuvant therapy for high-risk melanoma. Cancer Med 6:2576-2585
Himelstein, Andrew L; Foster, Jared C; Khatcheressian, James L et al. (2017) Effect of Longer-Interval vs Standard Dosing of Zoledronic Acid on Skeletal Events in Patients With Bone Metastases: A Randomized Clinical Trial. JAMA 317:48-58
Heinrich, Michael C; Rankin, Cathryn; Blanke, Charles D et al. (2017) Correlation of Long-term Results of Imatinib in Advanced Gastrointestinal Stromal Tumors With Next-Generation Sequencing Results: Analysis of Phase 3 SWOG Intergroup Trial S0033. JAMA Oncol 3:944-952
Cushman, Stephanie M; Jiang, Chen; Hatch, Ace J et al. (2015) Gene expression markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance). Clin Cancer Res 21:1078-86
Rugo, Hope S; Barry, William T; Moreno-Aspitia, Alvaro et al. (2015) Randomized Phase III Trial of Paclitaxel Once Per Week Compared With Nanoparticle Albumin-Bound Nab-Paclitaxel Once Per Week or Ixabepilone With Bevacizumab As First-Line Chemotherapy for Locally Recurrent or Metastatic Breast Cancer: CALGB 40502/NCCTG N0 J Clin Oncol 33:2361-9
Blumenthal, Deborah T; Rankin, Cathryn; Stelzer, Keith J et al. (2015) A Phase III study of radiation therapy (RT) and O?-benzylguanine + BCNU versus RT and BCNU alone and methylation status in newly diagnosed glioblastoma and gliosarcoma: Southwest Oncology Group (SWOG) study S0001. Int J Clin Oncol 20:650-8
Du, Juan; Lopez-Verges, Sandra; Pitcher, Brandelyn N et al. (2014) CALGB 150905 (Alliance): rituximab broadens the antilymphoma response by activating unlicensed NK cells. Cancer Immunol Res 2:878-89
Flaherty, Lawrence E; Othus, Megan; Atkins, Michael B et al. (2014) Southwest Oncology Group S0008: a phase III trial of high-dose interferon Alfa-2b versus cisplatin, vinblastine, and dacarbazine, plus interleukin-2 and interferon in patients with high-risk melanoma--an intergroup study of cancer and leukemia Group B, Ch J Clin Oncol 32:3771-8
Rizzieri, David A; Johnson, Jeffrey L; Byrd, John C et al. (2014) Improved efficacy using rituximab and brief duration, high intensity chemotherapy with filgrastim support for Burkitt or aggressive lymphomas: cancer and Leukemia Group B study 10 002. Br J Haematol 165:102-11
Smith, Matthew R; Halabi, Susan; Ryan, Charles J et al. (2014) Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases: results of CALGB 90202 (alliance). J Clin Oncol 32:1143-50

Showing the most recent 10 out of 68 publications