The objectives of this proposal are to support and enhance the current and future activities of New York University Medical Center (NYUMC) as a principal member of the Children's Cancer Group (CCG) by: (1) Improving the outcome for children with cancer through, a) continued patient entries at an increasing level to active CCG protocols, b) participation in leadership positions on CCG Strategy Groups and Discipline Committees so as to develop improved methods of treating childhood cancer, c) collaborating in the development of new studies by NYUMC investigators. 2) Developing new methodologies for the treatment of childhood cancer by, a) participation and leadership roles in Phase II studies and New Agent Phase I studies, b) piloting studies that have potential for incorporation into future CCG trials in selected disease entities such as brain tumors. 3) Improving the quality of life for survivors of childhood cancer and their families by, a) participating in CCG long-term effects studies, b) evaluating quality of life issues in children being treated for cancer, c) placing all eligible patients on open supportive care studies, d) continued participation in the cardiac intervention study conducted by the Children's Hospital of Philadelphia. 4) Active participation in biology studies by, a) timely and complete submission of biology samples and data, b) participation of NYUMC scientists and laboratories in studies involving cytogenetics, molecular biology and other laboratory disciplines. 5) Increasing the network of affiliated institutions relating to NYUMC so as to recruit patients for study who are currently not available for clinical trials. This includes the affiliation with Brooklyn Hospital and the recent affiliation with Maimonides Hospital- both caring for urban minority populations not otherwise participating in clinical trials.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA079753-02
Application #
6124652
Study Section
Subcommittee G - Education (NCI)
Program Officer
Smith, Malcolm M
Project Start
1999-06-10
Project End
2002-11-30
Budget Start
1999-12-01
Budget End
2000-11-30
Support Year
2
Fiscal Year
2000
Total Cost
$92,683
Indirect Cost
Name
New York University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016