Abstract

In this country, more patients are treated for alcohol and drug abuse by community-based treatment programs than by any other provider. While community treatment programs (CTPs) have a long history of providing quality treatment to large and diverse patient populations, their treatment approaches typically are not based on the latest evidence from the scientific literature. On the other hand, scientifically tested treatments, delivered under carefully controlled situations to highly selected patient groups, may not have applicability under usual care conditions. There is an urgent need to determine if research findings obtained in resource-rich universities are valid in community-based settings. The purpose of this application is to create a Rocky Mountain Regional (RMR) Clinical Trials Node to pursue this goal. Specifically, we offer the expertise of the substance abuse researchers in the Department of Psychiatry at the University of Colorado Health Sciences Center and the treatment providers we have been affiliated with for many years. Five of these providers are committed to participating in year one of the RMR Node and five more in year two, including CTPs from the state of Utah. Our affiliated treatment providers treat a broad array of clients with substance use problems in a variety of treatment modalities. We are committed to working in true partnership with Colorado and Utah CTPs and to working collaboratively with other investigators in NIDA's Clinical Trials Network (CTN), and with officials from NIDA. We have extensive and broad experience in multi-site collaborations, including multi-site clinical trials. We have expertise in a variety of behavioral and pharmacological treatment approaches, including motivational enhancement therapy, one of the interventions the CTN will be testing in the upcoming year. Our knowledge of this intervention in motivating out-of-treatment injection drug users to enter and remain in treatment would be of great benefit to the CTN.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10DA013716-03
Application #
6523226
Study Section
Special Emphasis Panel (ZDA1-WXG-F (27))
Program Officer
Tai, Betty
Project Start
2000-09-30
Project End
2005-08-31
Budget Start
2002-09-01
Budget End
2003-08-31
Support Year
3
Fiscal Year
2002
Total Cost
$1,800,000
Indirect Cost

  Institution

Name
University of Colorado Denver
Department
Psychiatry
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Serafini, Kelly; Decker, Suzanne; Kiluk, Brian D et al. (2015) Outcome expectations and associated treatment outcomes in motivational enhancement therapy delivered in English and Spanish. Am J Addict 24:732-9
Tamm, Leanne; Trello-Rishel, Kathlene; Riggs, Paula et al. (2013) Predictors of treatment response in adolescents with comorbid substance use disorder and attention-deficit/hyperactivity disorder. J Subst Abuse Treat 44:224-30
Hillhouse, Maureen; Canamar, Catherine P; Ling, Walter (2013) Predictors of outcome after short-term stabilization with buprenorphine. J Subst Abuse Treat 44:336-42
Warden, Diane; Riggs, Paula D; Min, Sung-Joon et al. (2012) Major depression and treatment response in adolescents with ADHD and substance use disorder. Drug Alcohol Depend 120:214-9
Tamm, Leanne; Adinoff, Bryon; Nakonezny, Paul A et al. (2012) Attention-deficit/hyperactivity disorder subtypes in adolescents with comorbid substance-use disorder. Am J Drug Alcohol Abuse 38:93-100
Riggs, Paula D; Winhusen, Theresa; Davies, Robert D et al. (2011) Randomized controlled trial of osmotic-release methylphenidate with cognitive-behavioral therapy in adolescents with attention-deficit/hyperactivity disorder and substance use disorders. J Am Acad Child Adolesc Psychiatry 50:903-14
Booth, Robert E; Campbell, Barbara K; Mikulich-Gilbertson, Susan K et al. (2011) Reducing HIV-related risk behaviors among injection drug users in residential detoxification. AIDS Behav 15:30-44
Gray, Kevin M; Riggs, Paula D; Min, Sung-Joon et al. (2011) Cigarette and cannabis use trajectories among adolescents in treatment for attention-deficit/hyperactivity disorder and substance use disorders. Drug Alcohol Depend 117:242-7
Campbell, Barbara K; Tillotson, Carrie J; Choi, Dongseok et al. (2010) Predicting outpatient treatment entry following detoxification for injection drug use: the impact of patient and program factors. J Subst Abuse Treat 38 Suppl 1:S87-96
Suarez-Morales, Lourdes; Martino, Steve; Bedregal, Luis et al. (2010) Do therapist cultural characteristics influence the outcome of substance abuse treatment for Spanish-speaking adults? Cultur Divers Ethnic Minor Psychol 16:199-205

Showing the most recent 10 out of 27 publications