1) To determine the natural history of subfoveal choroidal neovascular membranes in patients with ocular histoplasmosis and senile macular choroidal degeneration. 2) To determine by means of a collaborative, randomized clinical trial whether argon laser photocoagulation for extrafoveal choroidal neovascularization can prevent visual acuity loss in patients with ocular histoplasmosis and senile macular choroidal degeneration. 3) To document the natural course of serous detachments of the retinal pigment epithelium in eyes with senile macular choroidal degeneration. 4) To document the natural course of macular """"""""histo spots"""""""" and macular drusen in fellow eyes of patients with choroidal neovascularization in the first eye. 5) To develop a randomized, controlled clinical trial for subfoveal choroidal neovascularization in ocular histoplasmosis and senile macular choroidal degeneration and to develop a randomized clinical trial for serous detachments of the retinal pigment epithelium in senile macular choroidal degeneration pending the outcome of the natural history studies mentioned above.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10EY003288-13
Application #
3559104
Study Section
Vision Research and Training Committee (VSN)
Project Start
1979-09-30
Project End
1993-12-31
Budget Start
1992-01-01
Budget End
1992-12-31
Support Year
13
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Ingalls Memorial Hospital
Department
Type
DUNS #
City
Harvey
State
IL
Country
United States
Zip Code
60426