This is an application to become one of the cooperating clinics in the Optic Neuritis Treatment Trial. The ONTT consist of essentially two research components: (1) a clinical trial of the efficacy of oral prednisone and intravenous methylprednisolone in reducing residual optic nerve damage in patients with optic neuritis; and (2) a study of the natural history of optic neuritis. In this proposal we document our patient recruitment potential. Our group of ophthalmologists saw 7 patients with optic neuritis meeting the listed Study criteria within a 12 month period. In addition we provide data from 10 ophthalmologists in our referral area, willing to refer patients for the Study, who have seen a total of 23 patients with optic neuritis meeting the Study criteria within a 12 month period. We plan to contact our neurologists and other neurologists within our referral area should we be funded.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10EY007679-03
Application #
3559634
Study Section
Vision Research and Training Committee (VSN)
Project Start
1988-03-01
Project End
1992-02-29
Budget Start
1990-03-01
Budget End
1991-02-28
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030