Abstract

The Reproductive Medicine Unit (RMU) at the University of Alabama at Birmingham has been a member of the Cooperative Multicenter Reproductive Medicine Network since 1995. The Birmingham RMU has been highly productive with respect to subject recruitment, protocol design and administration, and minority involvement. For this competitive renewal application, a team of physicians and scientists experienced in a wide variety of clinical research in women's health has been assembled. With the diverse special facilities and programs available to the applicants, the Birmingham RMU is uniquely qualified to help accomplish the large-scale multicenter clinical trials for which the Reproductive Medicine Network was designed.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10HD033172-08
Application #
6520971
Study Section
Special Emphasis Panel (ZHD1-DRG-D (05))
Program Officer
Parrott, Estella C
Project Start
1995-04-01
Project End
2005-03-31
Budget Start
2002-04-01
Budget End
2003-03-31
Support Year
8
Fiscal Year
2002
Total Cost
$270,859
Indirect Cost

  Institution

Name
University of Alabama Birmingham
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Kuang, Hongying; Jin, Susan; Thomas, Tracey et al. (2015) Predictors of participant retention in infertility treatment trials. Fertil Steril 104:1236-43.e1-2
Polotsky, Alex J; Allshouse, Amanda A; Casson, Peter R et al. (2015) Impact of Male and Female Weight, Smoking, and Intercourse Frequency on Live Birth in Women With Polycystic Ovary Syndrome. J Clin Endocrinol Metab 100:2405-12
Kuang, Hongying; Jin, Susan; Hansen, Karl R et al. (2015) Identification and replication of prediction models for ovulation, pregnancy and live birth in infertile women with polycystic ovary syndrome. Hum Reprod 30:2222-33
Legro, Richard S; Brzyski, Robert G; Diamond, Michael P et al. (2014) The Pregnancy in Polycystic Ovary Syndrome II study: baseline characteristics and effects of obesity from a multicenter randomized clinical trial. Fertil Steril 101:258-269.e8
Legro, Richard S; Chen, Gang; Kunselman, Allen R et al. (2014) Smoking in infertile women with polycystic ovary syndrome: baseline validation of self-report and effects on phenotype. Hum Reprod 29:2680-6
Legro, Richard S; Kunselman, Allen R; Brzyski, Robert G et al. (2012) The Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) trial: rationale and design of a double-blind randomized trial of clomiphene citrate and letrozole for the treatment of infertility in women with polycystic ovary syndrome. Contemp Clin Trials 33:470-81
Leach, Richard E; Jessmon, Philip; Coutifaris, Christos et al. (2012) High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples. Hum Reprod 27:814-28
Roth, Lauren W; Huang, Hao; Legro, Richard S et al. (2012) Altering hirsutism through ovulation induction in women with polycystic ovary syndrome. Obstet Gynecol 119:1151-6
Diamond, Michael P; Kruger, Michael; Santoro, Nanette et al. (2012) Endometrial shedding effect on conception and live birth in women with polycystic ovary syndrome. Obstet Gynecol 119:902-8
Jones, Michelle R; Chua, Angela K; Mengesha, Emebet A et al. (2012) Metabolic and cardiovascular genes in polycystic ovary syndrome: a candidate-wide association study (CWAS). Steroids 77:317-22

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